50-167-1290

LGR5 Mouse anti-Human, Mouse, DyLight™ 488, Clone: OTI2A2, liquid, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-167-1290-Each-of-1 In Stock ₹ 47,857.99

50-167-1290 - Each of 1

₹ 47,857.99

In Stock

Quantity

1

Base Price: ₹ 47,857.99

GST (18%): ₹ 8,614.438

Total Price: ₹ 56,472.428

Antigen

LGR5

Classification

Monoclonal

Concentration

0.73 mg/mL

Formulation

PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O75473, Q9Z1P4

Gene Symbols

Lgr5

Immunogen

Human recombit protein fragment corresponding to amino acids 250-550 of human LGR5 produced in HEK293T Cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone

OTI2A2

Conjugate

DyLight 488

Gene

LGR5

Gene Alias

FEX, GPR49, GPR67, GRP49, HG38

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14160, 8549

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • G protein-coupled receptor GPR49 has been reported to be expressed in brain, skeletal muscle, placenta, and spinal cord
  • ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain libraries
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This ""turn-off"" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

Img

OriGene

50-167-1290

--


Antigen:
LGR5

Classification:
Monoclonal

Concentration:
0.73 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O75473, Q9Z1P4

Gene Symbols:
Lgr5

Immunogen:
Human recombit protein fragment corresponding to amino acids 250-550 of human LGR5 produced in HEK293T Cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone:
OTI2A2

Conjugate:
DyLight 488

Gene:
LGR5

Gene Alias:
FEX, GPR49, GPR67, GRP49, HG38

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14160, 8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-1292

--


Antigen:
BCL10

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O95999

Gene Symbols:
BCL10

Immunogen:
Full length human recombit protein of human BCL10 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
OTI4A8

Conjugate:
PE

Gene:
BCL10

Gene Alias:
c-E10, CARMEN, CIPER, CLAP, IMD37, mE10

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8915

Content And Storage:
4° C

Form:
Liquid

Img

OriGene

50-167-1294

--


Antigen:
LGR5

Classification:
Monoclonal

Concentration:
0.73 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O75473, Q9Z1P4

Gene Symbols:
LGR5

Immunogen:
Human recombit protein fragment corresponding to amino acids 250-550 of human LGR5 produced in HEK293T Cell.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2A2

Conjugate:
HRP

Gene:
LGR5

Gene Alias:
FEX, GPR49, GPR67, GRP49, HG38

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14160, 8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-1296

--


Antigen:
IDH1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O75874

Gene Symbols:
IDH1

Immunogen:
Full-length protein expressed in 293T cell transfected with human IDH1 expression vector

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2H9

Conjugate:
Biotin

Gene:
IDH1

Gene Alias:
HEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC, PICD

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3417

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid