50-167-1677

BUB1B Mouse anti-Human, Clone: OTI11D7, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-1677-Each-of-1 In Stock ₹ 43,217.21

50-167-1677 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

BUB1B

Classification

Monoclonal

Conjugate

Unconjugated

Gene

BUB1B

Gene Alias

BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

701

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI11D7

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O60566

Gene Symbols

BUB1B

Immunogen

Full-length protein expressed in 293T cell transfected with human BUB1B expression vector

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • BUBR1 is a member of the Ser/Thr protein kinase family
  • It is a component of the mitotic checkpoint that delays anaphase until all chromosome are properly attached to the mitotic spindle
  • Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to maligt transformations
  • Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
  • They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
  • hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
  • BUBR1 has been detected in human cancers
  • It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.

Compare Similar Items

Show Difference

Img

OriGene

50-167-1677

--


Antigen:
BUB1B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BUB1B

Gene Alias:
BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
701

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI11D7

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O60566

Gene Symbols:
BUB1B

Immunogen:
Full-length protein expressed in 293T cell transfected with human BUB1B expression vector

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-1678

--


Antigen:
STAT1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
STAT1

Gene Alias:
CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
488449, 6772

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4H9

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P42224

Gene Symbols:
STAT1

Immunogen:
Full length human recombit protein of human STAT1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-1679

--


Antigen:
DHFR

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
DHFR

Gene Alias:
DHFRP1, DYR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1719, 479165

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6G7

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P00374

Gene Symbols:
DHFR

Immunogen:
Full-length protein expressed in 293T cell transfected with human DHFR expression vector

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-1683

--


Antigen:
SATB1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SATB1

Gene Alias:
SATB homeobox 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6304

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI6C6

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q01826

Gene Symbols:
SATB1

Immunogen:
Full-length protein expressed in 293T cell transfected with human SATB1 expression vector

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1