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50-167-2092

CUGBP1 Mouse anti-Human, Clone: OTI5B8, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-2092-Each-of-1 In Stock ₹ 43,217.21

50-167-2092 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

CUGBP1

Classification

Monoclonal

Concentration

0.99 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q92879

Gene Symbols

CELF1

Immunogen

Full length human recombit protein of human CUGBP1 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI5B8

Conjugate

Unconjugated

Gene

CELF1

Gene Alias

BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10658

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Myotonic dystrophy (MD) is an autosomal domit neuromuscular disease that is associated with a (CTG)n repeat expansion in the 3′-untranslated region of the myotonin protein kinase (Mt-PK) gene
  • A (CUG) n oligonucleotides triplet repeat pre-mRNA/mRNA binding protein may play an important role in DM pathogenesis
  • HeLa cell protein, CUG-BP1, has been purified based upon its ability to bind specifically to (CUG) 8 oligonucleotides in vitro
  • CUG-BP1 is the major (CUG) 8 binding activity in normal cells
  • CUG-BP1 has been identified as isoforms of a novel heterogeneous nuclear ribonucleoprotein (hnRNP), hNab50
  • The CUG-BP/hNab50 protein is localized predomitly in the nucleus and is associated with polyadenylated RNAs in vivo
  • In vitro RNA-binding/photocrosslinking studies demonstrate that CUG-BP/hNab50 binds to RNAs containing the Mt-PK 3-UTR
  • The (CUG) n repeat region in Mt-PK mRNA is a binding site for CUG-BP/hNab50 in vivo, and triplet repeat expansion leads to sequestration of this hnRNP on mutant Mt-PK transcripts.

Compare Similar Items

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Img

OriGene

50-167-2092

--

Antigen:
CUGBP1
Classification:
Monoclonal
Concentration:
0.99 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q92879
Gene Symbols:
CELF1
Immunogen:
Full length human recombit protein of human CUGBP1 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI5B8
Conjugate:
Unconjugated
Gene:
CELF1
Gene Alias:
BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10658
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

Fischer Scientific

50-167-2094

--

Antigen:
RALBP1
Classification:
Monoclonal
Concentration:
0.8 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q15311
Gene Symbols:
RALBP1
Immunogen:
Full length human recombit protein of human RALBP1 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
OTI1E2
Conjugate:
Unconjugated
Gene:
RALBP1
Gene Alias:
RIP1, RLIP1, RLIP76
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10928
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

Fischer Scientific

50-167-2095

--

Antigen:
RALBP1
Classification:
Monoclonal
Concentration:
0.85 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q15311
Gene Symbols:
RALBP1
Immunogen:
Full length human recombit protein of human RALBP1 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
OTI6E8
Conjugate:
Unconjugated
Gene:
RALBP1
Gene Alias:
RIP1, RLIP1, RLIP76
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10928
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

Fischer Scientific

50-167-2098

--

Antigen:
NPR3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P17342
Gene Symbols:
NPR3
Immunogen:
Full length human recombit protein of human NPR3 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2G2
Conjugate:
Unconjugated
Gene:
NPR3
Gene Alias:
ANP-C, ANPR-C, ANPRC, C5orf23, GUCY2B, NPR-C, NPRC
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4883
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid