50-167-4287
DOK2 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI2D10, liquid, TrueMAB™
Manufacturer: OriGene
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-4287-Each-of-1 | In Stock | ₹ 43,217.21 |
50-167-4287 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
DOK2
Classification
Monoclonal
Concentration
0.43 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
O60496, O70469
Gene Symbols
Dok2
Immunogen
Full length human recombit protein of human DOK2 produced in HEK293T cell.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
OTI2D10
Conjugate
Unconjugated
Gene
DOK2
Gene Alias
p56DOK, p56dok-2
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13449, 290361, 486133, 9046
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Description
- Docking proteins interact with receptor tyrosine kinases and mediate particular biological responses using signal transduction
- Dok-2 acts as a multiple docking protein downstream of receptor or non-receptor tyrosine kinases
- By this mechanism it acts to negatively regulate signal transduction and cell proliferation controlled by cytokines in a feedback loop
- Dok-2 is highly expressed in cells and tissues of hematopoietic origin as well as in lung
- Expression of bcr/abl induces additional tyrosine phosphorylation of the Dok1 and Dok2 proteins and their association with Ras-GAP
- Thus, it is suspected that DOK association regulates GAP activity toward Ras and that the Dok proteins serve as mediators of bcr-abl signaling
- The role of Dok proteins in bcr-abl regulation may also be implicated in chronic myelogenous leukemia (CML), which is characterized by a Philadelphia chromosome translocation t(9;22)
- Such a mutation would result in a p210-bcr/abl chimeric protein-tyrosine kinase which has been found in many CML cases.
Compare Similar Items
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Antigen: DOK2
Classification: Monoclonal
Concentration: 0.43 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O60496, O70469
Gene Symbols: Dok2
Immunogen: Full length human recombit protein of human DOK2 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI2D10
Conjugate: Unconjugated
Gene: DOK2
Gene Alias: p56DOK, p56dok-2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13449, 290361, 486133, 9046
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
DOK2
Classification:
Monoclonal
Concentration:
0.43 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O60496, O70469
Gene Symbols:
Dok2
Immunogen:
Full length human recombit protein of human DOK2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI2D10
Conjugate:
Unconjugated
Gene:
DOK2
Gene Alias:
p56DOK, p56dok-2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13449, 290361, 486133, 9046
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: IRF6
Classification: Monoclonal
Concentration: 0.73 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O14896
Gene Symbols: IRF6
Immunogen: Full length human recombit protein of human IRF6 produced in HEK293 cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI1G3
Conjugate: Unconjugated
Gene: IRF6
Gene Alias: LPS, OFC6, PIT, PPS, PPS1, VWS, VWS1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3664
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
IRF6
Classification:
Monoclonal
Concentration:
0.73 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O14896
Gene Symbols:
IRF6
Immunogen:
Full length human recombit protein of human IRF6 produced in HEK293 cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI1G3
Conjugate:
Unconjugated
Gene:
IRF6
Gene Alias:
LPS, OFC6, PIT, PPS, PPS1, VWS, VWS1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3664
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ATG3
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q9NT62
Gene Symbols: ATG3
Immunogen: Full length human recombit protein of human ATG3 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI3H1
Conjugate: Unconjugated
Gene: ATG3
Gene Alias: APG3, APG3-LIKE, APG3L, PC3-96
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64422
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ATG3
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9NT62
Gene Symbols:
ATG3
Immunogen:
Full length human recombit protein of human ATG3 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI3H1
Conjugate:
Unconjugated
Gene:
ATG3
Gene Alias:
APG3, APG3-LIKE, APG3L, PC3-96
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64422
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ATG3
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q9NT62
Gene Symbols: ATG3
Immunogen: Full length human recombit protein of human ATG3 produced in HEK293 cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI2B9
Conjugate: Unconjugated
Gene: ATG3
Gene Alias: APG3, APG3-LIKE, APG3L, PC3-96
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64422
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ATG3
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9NT62
Gene Symbols:
ATG3
Immunogen:
Full length human recombit protein of human ATG3 produced in HEK293 cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI2B9
Conjugate:
Unconjugated
Gene:
ATG3
Gene Alias:
APG3, APG3-LIKE, APG3L, PC3-96
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64422
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid