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50-167-4393

ERBB2 Mouse anti-Human, Clone: OTI3F11, liquid, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-167-4393-Each-of-1 In Stock ₹ 43,217.21

50-167-4393 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

ERBB2

Classification

Monoclonal

Concentration

0.88 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P04626

Gene Symbols

ERBB2

Immunogen

Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI3F11

Conjugate

Unconjugated

Gene

ERBB2

Gene Alias

CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2064

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • ErbB2 (Her2/neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR (epidermal growth factor receptor) family that regulates biological responses such as cell growth, differentiation, and tissue development
  • ErbB2 has no ligand binding domain of its own and cannot bind growth factors
  • However, ErbB2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase
  • Autophosphorylation of tyrosine 1139 on ErbB2 allows binding of Grb2 and the Src SH2 domain, which allows activation of the Ras, Raf, ERK1/2 and JAK/STAT signaling pathways, respectively
  • Alternative splicing of ErbB2 results in several transcript variants, some encoding different isoforms and others that have not been fully characterized
  • In humans, the gene encoding ERBB2 is present on chromosome 17
  • Amplification and/or overexpression of the ErbB2 gene has been reported in ovarian tumors, breast, lung and skin cancer.

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Img

OriGene

50-167-4393

--

Antigen:
ERBB2
Classification:
Monoclonal
Concentration:
0.88 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI3F11
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

Fischer Scientific

50-167-4395

--

Antigen:
ERBB2
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI12G4
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

Fischer Scientific

50-167-4396

--

Antigen:
PPARA
Classification:
Monoclonal
Concentration:
0.48 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q07869
Gene Symbols:
PPARA
Immunogen:
Human recombit protein fragment corresponding to amino acids 145-420 of human PPARA produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI2D10
Conjugate:
Unconjugated
Gene:
PPARA
Gene Alias:
NR1C1, PPAR, PPARalpha, hPPAR
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5465
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

Fischer Scientific

50-167-4397

--

Antigen:
PDE4B
Classification:
Monoclonal
Concentration:
0.73 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q07343
Gene Symbols:
PDE4B
Immunogen:
Full length human recombit protein of human PDE4B produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI3A10
Conjugate:
Unconjugated
Gene:
PDE4B
Gene Alias:
DPDE4, PDEIVB
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5142
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid