50-167-6657
PTPRC Monoclonal Antibody (OTI1B6), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-6657-Each-of-1 | In Stock | ₹ 43,217.21 |
50-167-6657 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
PTPRC
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P08575
Gene Symbols
PTPRC
Immunogen
Full length human recombit protein of human PTPRC produced in HEK293T cell.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI1B6
Conjugate
Unconjugated
Gene
PTPRC
Gene Alias
B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; HCD45
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5788
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
- CD45 is absent on non-hematopoietic cell lines, normal and maligt, non-hematopoietic tissues
- CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
- CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
- CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
- CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
- CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.
Compare Similar Items
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Antigen: PTPRC
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P08575
Gene Symbols: PTPRC
Immunogen: Full length human recombit protein of human PTPRC produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1B6
Conjugate: Unconjugated
Gene: PTPRC
Gene Alias: B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; HCD45
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5788
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PTPRC
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P08575
Gene Symbols:
PTPRC
Immunogen:
Full length human recombit protein of human PTPRC produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1B6
Conjugate:
Unconjugated
Gene:
PTPRC
Gene Alias:
B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; HCD45
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: TH
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P07101
Gene Symbols: TH
Immunogen: Full length human recombit protein of human TH produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1A12
Conjugate: Unconjugated
Gene: TH
Gene Alias: DYT14, DYT5b, TYH
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7054
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TH
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P07101
Gene Symbols:
TH
Immunogen:
Full length human recombit protein of human TH produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1A12
Conjugate:
Unconjugated
Gene:
TH
Gene Alias:
DYT14, DYT5b, TYH
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7054
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Immunogen: __
Quantity: __
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
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Quantity:
__
Primary or Secondary:
__
Target Species:
__
Product Type:
__
Isotype:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
__
Antigen: PTPRC
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P08575
Gene Symbols: PTPRC
Immunogen: Full length human recombit protein of human PTPRC produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI3E3
Conjugate: Unconjugated
Gene: PTPRC
Gene Alias: B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; HCD45
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5788
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PTPRC
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P08575
Gene Symbols:
PTPRC
Immunogen:
Full length human recombit protein of human PTPRC produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI3E3
Conjugate:
Unconjugated
Gene:
PTPRC
Gene Alias:
B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; HCD45
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid