50-167-6713

PMS2 Mouse anti-Human, Clone: OTI2G5, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-6713-Each-of-1 In Stock ₹ 43,217.21

50-167-6713 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

PMS2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P54278

Gene Symbols

PMS2

Immunogen

Full length human recombit protein of human PMS2 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2G5

Conjugate

Unconjugated

Gene

PMS2

Gene Alias

HNPCC4, MLH4, PMS2CL, PMSL2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5395

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

OriGene

50-167-6716

--

Img

OriGene

50-167-6031

--

Img

OriGene

50-167-6760

--

Img

OriGene

50-167-6644

--

Img

OriGene

50-167-6755

--

Img

OriGene

50-167-6474

--

Img

OriGene

50-167-6535

--

Img

OriGene

50-167-6531

--

Description

  • Mismatch DNA repair in bacteria is carried out by the MutL, MutH, and MutS proteins
  • The MutS protein initially binds to mismatched DNA
  • This is followed by binding of the MutH endonuclease and MutL to form a complex that carries out excision repair
  • The hMSH2 gene specifies a MutS homologue and hMLH1, hPMS1, and hPMS2 encode MutL homologs
  • Mutations in these genes are associated with hereditary nonpolyposis colon cancer (HNPCC), one of the most common hereditary diseases in man
  • As with the bacterial system, HNPCC is characterized by frequent microsatellite mutations that arise by somatic mutation due to a replication error (RER+) phenotype
  • Both hPMS1 and hPMS2 are mutated in the germline of HNPCC patients
  • Although the exact function of MutL and its homologs has yet to be determined, it is known that a complex of PMS2 and MLH1 (MutLa) from HeLa cells can complement a deficiency of MLH1 in hypermutable H6 colorectal tumor cells.

Compare Similar Items

Show Difference

Img

OriGene

50-167-6713

--


Antigen:
PMS2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P54278

Gene Symbols:
PMS2

Immunogen:
Full length human recombit protein of human PMS2 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2G5

Conjugate:
Unconjugated

Gene:
PMS2

Gene Alias:
HNPCC4, MLH4, PMS2CL, PMSL2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5395

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-6716

--


Antigen:
PMS2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P54278

Gene Symbols:
PMS2

Immunogen:
Full length human recombit protein of human PMS2 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4B7

Conjugate:
Unconjugated

Gene:
PMS2

Gene Alias:
HNPCC4, MLH4, PMS2CL, PMSL2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5395

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-6717

--


Antigen:
TUBB2B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9BVA1

Gene Symbols:
TUBB2B

Immunogen:
Full length human recombit protein of human TUBB2B produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8F12

Conjugate:
Unconjugated

Gene:
TUBB2B

Gene Alias:
CDCBM7, PMGYSA, bA506K6.1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
347733

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-6718

--


Antigen:
TUBA1C

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9BQE3

Gene Symbols:
TUBA1C

Immunogen:
Full length human recombit protein of human TUBA1C produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI1D8

Conjugate:
Unconjugated

Gene:
TUBA1C

Gene Alias:
TUBA6, bcm948

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84790

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid