50-167-7579
CHEK2 Mouse anti-Human, Biotin, Clone: OTI4C10, liquid, TrueMAB™
Manufacturer: OriGene
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-7579-Each-of-1 | In Stock | ₹ 47,761.30 |
50-167-7579 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,761.30
GST (18%): ₹ 8,597.034
Total Price: ₹ 56,358.334
Antigen
CHEK2
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
O96017
Gene Symbols
CHEK2
Immunogen
Full length human recombit protein of human CHEK2 produced in HEK293T cell.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA
Clone
OTI4C10
Conjugate
Biotin
Gene
CHEK2
Gene Alias
CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11200
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Checkpoint kinase 2 (Chk2) is a serine/threonine-protein kinase which functions as a cell cycle checkpoint regulator
- ATM and ATR kinases are activated in response to ionizing and ultraviolet radition, and phosphorylate Thr68 and other sites in the amino-terminal region of Chk2 dimerisation and activation
- Activated Chk2 phosphorylates and inhibits Cdc25C phosphates, preventing the entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
- In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
- Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
- Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.
Compare Similar Items
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Antigen: CHEK2
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: O96017
Gene Symbols: CHEK2
Immunogen: Full length human recombit protein of human CHEK2 produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA
Clone: OTI4C10
Conjugate: Biotin
Gene: CHEK2
Gene Alias: CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11200
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CHEK2
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
O96017
Gene Symbols:
CHEK2
Immunogen:
Full length human recombit protein of human CHEK2 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA
Clone:
OTI4C10
Conjugate:
Biotin
Gene:
CHEK2
Gene Alias:
CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11200
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: LDHA
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P00338
Gene Symbols: LDHA
Immunogen: Protein expressed in 293T cell transfected with human LDHA expression vector
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA
Clone: OTI2B11
Conjugate: Biotin
Gene: LDHA
Gene Alias: GSD11, HEL-S-133P, LDHM, PIG19
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3939
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
LDHA
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P00338
Gene Symbols:
LDHA
Immunogen:
Protein expressed in 293T cell transfected with human LDHA expression vector
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA
Clone:
OTI2B11
Conjugate:
Biotin
Gene:
LDHA
Gene Alias:
GSD11, HEL-S-133P, LDHM, PIG19
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3939
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: AKT2
Classification: Monoclonal
Concentration: __
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P31751
Gene Symbols: AKT2
Immunogen: Full length human recombit protein of human AKT2 produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: ELISA
Clone: OTI1A2
Conjugate: Biotin
Gene: AKT2
Gene Alias: HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 208
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
AKT2
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P31751
Gene Symbols:
AKT2
Immunogen:
Full length human recombit protein of human AKT2 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ELISA
Clone:
OTI1A2
Conjugate:
Biotin
Gene:
AKT2
Gene Alias:
HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
208
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: BRAF
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P15056
Gene Symbols: BRAF
Immunogen: Protein expressed in 293T cell transfected with human BRAF expression vector
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: ELISA
Clone: OTI3A7
Conjugate: Biotin
Gene: BRAF
Gene Alias: B-RAF1, B-raf, BRAF1, NS7, RAFB1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 673
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BRAF
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P15056
Gene Symbols:
BRAF
Immunogen:
Protein expressed in 293T cell transfected with human BRAF expression vector
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ELISA
Clone:
OTI3A7
Conjugate:
Biotin
Gene:
BRAF
Gene Alias:
B-RAF1, B-raf, BRAF1, NS7, RAFB1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
673
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid