50-167-7673
Beta-catenin Mouse anti-Human, Biotin, Clone: OTI12H7, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-7673-Each-of-1 | In Stock | ₹ 47,761.30 |
50-167-7673 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,761.30
GST (18%): ₹ 8,597.034
Total Price: ₹ 56,358.334
Antigen
Beta-catenin
Clone
OTI12H7
Conjugate
Biotin
Gene
CTNNB1
Gene Alias
CTNNB, EVR7, MRD19, armadillo
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1499
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
P35222
Gene Symbols
CTNNB1
Immunogen
Full length human recombit protein of human CTNNB1 produced in HEK293T cell.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Description
- Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
- AJs are necessary for the creation and maintece of epithelial cell layers by regulating cell growth and adhesion between cells
- Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
- Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
- The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
- Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
- A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
- In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
- The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.
Compare Similar Items
Show Difference
Antigen: Beta-catenin
Clone: OTI12H7
Conjugate: Biotin
Gene: CTNNB1
Gene Alias: CTNNB, EVR7, MRD19, armadillo
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1499
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P35222
Gene Symbols: CTNNB1
Immunogen: Full length human recombit protein of human CTNNB1 produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
Beta-catenin
Clone:
OTI12H7
Conjugate:
Biotin
Gene:
CTNNB1
Gene Alias:
CTNNB, EVR7, MRD19, armadillo
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1499
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P35222
Gene Symbols:
CTNNB1
Immunogen:
Full length human recombit protein of human CTNNB1 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: PRL
Clone: OTI6B1
Conjugate: Biotin
Gene: PRL
Gene Alias: GHA1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5617
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P01236
Gene Symbols: PRL
Immunogen: Full length human recombit protein of human PRL produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
PRL
Clone:
OTI6B1
Conjugate:
Biotin
Gene:
PRL
Gene Alias:
GHA1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5617
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P01236
Gene Symbols:
PRL
Immunogen:
Full length human recombit protein of human PRL produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: LDLRAP1
Clone: OTI4B10
Conjugate: Biotin
Gene: LDLRAP1
Gene Alias: ARH, ARH1, ARH2, FHCB1, FHCB2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26119
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q5SW96
Gene Symbols: LDLRAP1
Immunogen: Full length human recombit protein of human LDLRAP1 produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
LDLRAP1
Clone:
OTI4B10
Conjugate:
Biotin
Gene:
LDLRAP1
Gene Alias:
ARH, ARH1, ARH2, FHCB1, FHCB2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26119
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q5SW96
Gene Symbols:
LDLRAP1
Immunogen:
Full length human recombit protein of human LDLRAP1 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: LDLRAP1
Clone: OTI5A12
Conjugate: Biotin
Gene: LDLRAP1
Gene Alias: ARH, ARH1, ARH2, FHCB1, FHCB2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26119
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q5SW96
Gene Symbols: LDLRAP1
Immunogen: Full length human recombit protein of human LDLRAP1 produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
LDLRAP1
Clone:
OTI5A12
Conjugate:
Biotin
Gene:
LDLRAP1
Gene Alias:
ARH, ARH1, ARH2, FHCB1, FHCB2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26119
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q5SW96
Gene Symbols:
LDLRAP1
Immunogen:
Full length human recombit protein of human LDLRAP1 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1