50-167-7728
ERBB2 Mouse anti-Human, Biotin, Clone: OTI11A7, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-7728-Each-of-1 | In Stock | ₹ 47,761.30 |
50-167-7728 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,761.30
GST (18%): ₹ 8,597.034
Total Price: ₹ 56,358.334
Antigen
ERBB2
Clone
OTI11A7
Conjugate
Biotin
Gene
ERBB2
Gene Alias
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2064
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
P04626
Gene Symbols
ERBB2
Immunogen
Full length human recombit protein of human ERBB2 produced in HEK293T cell.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Description
- ErbB2 (Her2/neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR (epidermal growth factor receptor) family that regulates biological responses such as cell growth, differentiation, and tissue development
- ErbB2 has no ligand binding domain of its own and cannot bind growth factors
- However, ErbB2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase
- Autophosphorylation of tyrosine 1139 on ErbB2 allows binding of Grb2 and the Src SH2 domain, which allows activation of the Ras, Raf, ERK1/2 and JAK/STAT signaling pathways, respectively
- Alternative splicing of ErbB2 results in several transcript variants, some encoding different isoforms and others that have not been fully characterized
- In humans, the gene encoding ERBB2 is present on chromosome 17
- Amplification and/or overexpression of the ErbB2 gene has been reported in ovarian tumors, breast, lung and skin cancer.
Compare Similar Items
Show Difference
Antigen: ERBB2
Clone: OTI11A7
Conjugate: Biotin
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: Full length human recombit protein of human ERBB2 produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
ERBB2
Clone:
OTI11A7
Conjugate:
Biotin
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Full length human recombit protein of human ERBB2 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: ERBB2
Clone: OTI4G7
Conjugate: Biotin
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: Full length human recombit protein of human ERBB2 produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
ERBB2
Clone:
OTI4G7
Conjugate:
Biotin
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Full length human recombit protein of human ERBB2 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: ERBB2
Clone: OTI4F6
Conjugate: Biotin
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: Full length human recombit protein of human ERBB2 produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
ERBB2
Clone:
OTI4F6
Conjugate:
Biotin
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Full length human recombit protein of human ERBB2 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: ENG
Clone: OTI3D5
Conjugate: Biotin
Gene: ENG
Gene Alias: END, HHT1, ORW1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2022
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P17813
Gene Symbols: ENG
Immunogen: Full length human recombit protein of human ENG produced in HEK293T cell.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
ENG
Clone:
OTI3D5
Conjugate:
Biotin
Gene:
ENG
Gene Alias:
END, HHT1, ORW1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2022
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P17813
Gene Symbols:
ENG
Immunogen:
Full length human recombit protein of human ENG produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1