50-167-8022

RYBP Monoclonal Antibody (OTI1B6), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-8022-Each-of-1 In Stock ₹ 43,217.21

50-167-8022 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

RYBP

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q8N488

Gene Symbols

RYBP

Immunogen

Full length human recombit protein of human RYBP produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Western Blot

Clone

OTI1B6

Conjugate

Unconjugated

Gene

RYBP

Gene Alias

AAP1, APAP-1, DEDAF, YEAF1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23429

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • RYBP involves component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development
  • PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ′Lys-119′, rendering chromatin heritably changed in its expressibility
  • Component of a PRC1-like complex that mediates monoubiquitination of histone H2A ′Lys-119′ on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females
  • May stimulate ubiquitination of histone H2A ′Lys-119′ by recruiting the complex to target sites
  • Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes
  • May also regulate the ubiquitin-mediated proteasomal degradation of other proteins like FANK1 to regulate apoptosis
  • May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1
  • May bind to DNA
  • May play a role in the repression of tumor growth and metastasis in breast cancer by down-regulating SRRM3.

Compare Similar Items

Show Difference

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OriGene

50-167-8022

--


Antigen:
RYBP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8N488

Gene Symbols:
RYBP

Immunogen:
Full length human recombit protein of human RYBP produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Western Blot

Clone:
OTI1B6

Conjugate:
Unconjugated

Gene:
RYBP

Gene Alias:
AAP1, APAP-1, DEDAF, YEAF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23429

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8023

--


Antigen:
RYBP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8N488

Gene Symbols:
RYBP

Immunogen:
Full length human recombit protein of human RYBP produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Western Blot

Clone:
OTI2H9

Conjugate:
Unconjugated

Gene:
RYBP

Gene Alias:
AAP1, APAP-1, DEDAF, YEAF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23429

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8024

--


Antigen:
DPPA4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q7L190

Gene Symbols:
DPPA4

Immunogen:
Human recombit protein fragment corresponding to amino acids 9-254 of human DPPA4 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Western Blot

Clone:
OTI2F6

Conjugate:
Unconjugated

Gene:
DPPA4

Gene Alias:
2410091M23Rik

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55211

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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OriGene

50-167-8025

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Antigen:
USP12

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O75317

Gene Symbols:
USP12

Immunogen:
Human recombit protein fragment corresponding to amino acids 61-251 of human USP12 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2A6

Conjugate:
Unconjugated

Gene:
USP12

Gene Alias:
UBH1, USP12L1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
219333

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid