50-167-8290

CUL4B Monoclonal Antibody (OTI7G10), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-8290-Each-of-1 In Stock ₹ 43,217.21

50-167-8290 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

CUL4B

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q13620

Gene Symbols

CUL4B

Immunogen

Human recombit protein fragment corresponding to amino acids 1-300 of human CUL4B produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI7G10

Conjugate

Unconjugated

Gene

CUL4B

Gene Alias

CUL-4B, MRXHF2, MRXS15, MRXSC, SFM2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8450

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

OriGene

50-168-2127

--

Img

OriGene

50-167-8437

--

Img

OriGene

50-167-8322

--

Img

OriGene

50-167-8326

--

Img

OriGene

50-167-8367

--

Img

OriGene

50-167-8036

--

Img

OriGene

50-167-7999

--

Img

OriGene

50-168-4431

--

Description

  • Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
  • The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit
  • CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme
  • Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage
  • Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication
  • Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression
  • Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism
  • Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8.

Compare Similar Items

Show Difference

Img

OriGene

50-167-8290

--


Antigen:
CUL4B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q13620

Gene Symbols:
CUL4B

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-300 of human CUL4B produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI7G10

Conjugate:
Unconjugated

Gene:
CUL4B

Gene Alias:
CUL-4B, MRXHF2, MRXS15, MRXSC, SFM2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8450

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8291

--


Antigen:
F13A1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P00488

Gene Symbols:
F13A1

Immunogen:
Full length human recombit protein of human F13A1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI8E2

Conjugate:
Unconjugated

Gene:
F13A1

Gene Alias:
F13A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8292

--


Antigen:
CD20 (MS4A1)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P11836

Gene Symbols:
MS4A1

Immunogen:
Full length human recombit protein of human MS4A1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1H4

Conjugate:
Unconjugated

Gene:
MS4A1

Gene Alias:
B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
931

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8293

--


Antigen:
EPHX1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P07099

Gene Symbols:
EPHX1

Immunogen:
Human recombit protein fragment corresponding to amino acids 21-230 of human EPHX1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3A10

Conjugate:
Unconjugated

Gene:
EPHX1

Gene Alias:
EPHX, EPOX, HYL1, MEH

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2052

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid