Home Products Antibodies Primary Antibodies 50 167 8388
50-167-8388

CD20 (MS4A1) Monoclonal Antibody (OTI11F7), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-8388-Each-of-1 In Stock ₹ 43,217.21

50-167-8388 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

CD20 (MS4A1)

Classification

Monoclonal

Conjugate

Unconjugated

Gene

MS4A1

Gene Alias

B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

931

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

OTI11F7

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P11836

Gene Symbols

MS4A1

Immunogen

Full length human recombit protein of human MS4A1 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Related Products

Img

OriGene

50-167-8363

--

Img

OriGene

50-167-8389

--

Img

OriGene

50-168-5147

--

Img

OriGene

50-167-8409

--

Img

OriGene

50-167-8401

--

Img

OriGene

50-167-8382

--

Img

OriGene

50-168-4479

--

Img

OriGene

50-167-4886

--

Description

  • CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation
  • CD20 is expressed on mature and most maligt B cells, in a subpopulation of T lymphocytes and follicular dendritic cells
  • CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation
  • CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation
  • After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface
  • CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell maligcies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment
  • Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.

Compare Similar Items

Show Difference

Img

OriGene

50-167-8388

--

Antigen:
CD20 (MS4A1)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MS4A1
Gene Alias:
B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
931
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI11F7
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P11836
Gene Symbols:
MS4A1
Immunogen:
Full length human recombit protein of human MS4A1 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1

Img

OriGene

50-167-8389

--

Antigen:
CD20 (MS4A1)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MS4A1
Gene Alias:
B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
931
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2C11
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P11836
Gene Symbols:
MS4A1
Immunogen:
Full length human recombit protein of human MS4A1 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b

Img

OriGene

50-167-8390

--

Antigen:
ZSCAN4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ZSCAN4
Gene Alias:
ZNF494
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
201516
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2C5
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q8NAM6
Gene Symbols:
ZSCAN4
Immunogen:
Human recombit protein fragment corresponding to amino acids 164-433 of human ZSCAN4 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1

Img

OriGene

50-167-8392

--

Antigen:
ZSCAN4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ZSCAN4
Gene Alias:
ZNF494
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
201516
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI1C6
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q8NAM6
Gene Symbols:
ZSCAN4
Immunogen:
Human recombit protein fragment corresponding to amino acids 164-433 of human ZSCAN4 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a