50-167-8496
CD2 Monoclonal Antibody (OTI2C3), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-8496-Each-of-1 | In Stock | ₹ 43,217.21 |
50-167-8496 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
CD2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P06729
Gene Symbols
CD2
Immunogen
Full length human recombit protein of human CD2 produced in HEK293T cell.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
OTI2C3
Conjugate
Unconjugated
Gene
CD2
Gene Alias
LFA-2, SRBC, T11
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
914
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
- CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
- Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
- The interaction betwee CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
- Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
- Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
- Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
- CD2 deficiency reduces intestinal inflammation and helps to control infection
- Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.
Compare Similar Items
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Antigen: CD2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P06729
Gene Symbols: CD2
Immunogen: Full length human recombit protein of human CD2 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI2C3
Conjugate: Unconjugated
Gene: CD2
Gene Alias: LFA-2, SRBC, T11
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 914
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CD2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P06729
Gene Symbols:
CD2
Immunogen:
Full length human recombit protein of human CD2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI2C3
Conjugate:
Unconjugated
Gene:
CD2
Gene Alias:
LFA-2, SRBC, T11
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
914
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SERBP1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q6AXS5, Q8NC51, Q9CY58
Gene Symbols: Serbp1
Immunogen: Human recombit protein fragment corresponding to amino acids 1-262 of human SERBP1 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2E11
Conjugate: Unconjugated
Gene: SERBP1
Gene Alias: CGI-55, CHD3IP, HABP4L, PAI-RBP1, PAIRBP1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 246303, 26135, 479535, 66870
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SERBP1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q6AXS5, Q8NC51, Q9CY58
Gene Symbols:
Serbp1
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-262 of human SERBP1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2E11
Conjugate:
Unconjugated
Gene:
SERBP1
Gene Alias:
CGI-55, CHD3IP, HABP4L, PAI-RBP1, PAIRBP1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
246303, 26135, 479535, 66870
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ALK
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q9UM73
Gene Symbols: ALK
Immunogen: Human recombit protein fragment corresponding to amino acids 1060-1620 of human ALK produced in SF9 cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI1F1
Conjugate: Unconjugated
Gene: ALK
Gene Alias: CD246, NBLST3
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 238
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ALK
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9UM73
Gene Symbols:
ALK
Immunogen:
Human recombit protein fragment corresponding to amino acids 1060-1620 of human ALK produced in SF9 cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI1F1
Conjugate:
Unconjugated
Gene:
ALK
Gene Alias:
CD246, NBLST3
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
238
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ALK
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q9UM73
Gene Symbols: ALK
Immunogen: Human recombit protein fragment corresponding to amino acids 1060-1620 of human ALK produced in SF9 cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI1B1
Conjugate: Unconjugated
Gene: ALK
Gene Alias: CD246, NBLST3
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 238
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ALK
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9UM73
Gene Symbols:
ALK
Immunogen:
Human recombit protein fragment corresponding to amino acids 1060-1620 of human ALK produced in SF9 cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI1B1
Conjugate:
Unconjugated
Gene:
ALK
Gene Alias:
CD246, NBLST3
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
238
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid