50-167-8666

KIT Monoclonal Antibody (OTI2B5), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-8666-Each-of-1 In Stock ₹ 43,217.21

50-167-8666 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

KIT

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P10721

Gene Symbols

KIT

Immunogen

Human recombit protein fragment corresponding to amino acids 546-976 of human KIT produced in SF9 cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI2B5

Conjugate

Unconjugated

Gene

KIT

Gene Alias

C-Kit, CD117, PBT, SCFR

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3815

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

OriGene

50-167-8701

--

Img

OriGene

50-167-8665

--

Img

OriGene

50-167-8893

--

Img

OriGene

50-167-8498

--

Img

OriGene

50-167-8499

--

Img

OriGene

50-167-8500

--

Img

OriGene

50-168-1687

--

Img

OriGene

50-168-1679

--

Description

  • c-Kit, also known as mast/stem cell growth factor receptor (SCFR) or CD117, is a trans membrane type III tyrosine kinase receptor encoded by the c-Kit proto-oncogene, located on chromosome 4 in humans
  • It is expressed in hematopoietic stem cells, germ cells, mast cells and gastrointestinal tract cajal cells
  • Upon binding of its ligand stem cell factor (SCF), c-kit dimerizes, resulting in receptor activation and autophosphorylation of various tyrosine residues including tyrosine 703 located on the cytoplasmic domain of the receptor
  • This modification allows docking of Grb2 and activation of the Ras/ERK signaling pathway
  • SCF/c-kit can activate multiple downstream signaling pathways including PI3K, PLC-gamma and JAK/STAT
  • c-kit receptor activation is essential for hematopoiesis, stem cell maintece and gametogenesis.

Compare Similar Items

Show Difference

Img

OriGene

50-167-8666

--


Antigen:
KIT

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P10721

Gene Symbols:
KIT

Immunogen:
Human recombit protein fragment corresponding to amino acids 546-976 of human KIT produced in SF9 cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2B5

Conjugate:
Unconjugated

Gene:
KIT

Gene Alias:
C-Kit, CD117, PBT, SCFR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3815

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8667

--


Antigen:
ABCB1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08183

Gene Symbols:
ABCB1

Immunogen:
Human recombit protein fragment corresponding to amino acids 995-1280 of human ABCB1 produced in SF9 cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1A3

Conjugate:
Unconjugated

Gene:
ABCB1

Gene Alias:
ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5243

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8668

--


Antigen:
FGFR3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P22607

Gene Symbols:
FGFR3

Immunogen:
Human recombit protein fragment corresponding to amino acids 23-375 of human FGFR3 produced in Insect.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI1G10

Conjugate:
Unconjugated

Gene:
FGFR3

Gene Alias:
ACH, CD333, CEK2, HSFGFR3EX, JTK4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2261

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8669

--


Antigen:
ABCB1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08183

Gene Symbols:
ABCB1

Immunogen:
Human recombit protein fragment corresponding to amino acids 995-1280 of human ABCB1 produced in SF9 cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI5D1

Conjugate:
Unconjugated

Gene:
ABCB1

Gene Alias:
ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5243

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid