50-167-8682

ESR2 Monoclonal Antibody (OTI1E12), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-8682-Each-of-1 In Stock ₹ 43,217.21

50-167-8682 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

ESR2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q92731

Gene Symbols

ESR2

Immunogen

Human recombit protein fragment corresponding to amino acids 1-260 of human ESR2 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI1E12

Conjugate

Unconjugated

Gene

ESR2

Gene Alias

ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2100

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described
  • Human ER beta was initially cloned and characterized from testis
  • Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
  • The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
  • When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
  • There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
  • Estrogen receptor beta (ER beta) binds estrogens with an affinity similar to that of estrogen receptor alpha
  • Some ER beta isoforms domitly inhibit the activity of estrogen receptor alpha in reproductive tissues
  • ER beta is found widely in many tissues throughout the body and can act as a potent tumor suppressor, playing a crucial role in many cancer types such as prostate cancer, autism spectrum disorder, medullary thyroid carcinoma, De Quervain Disease and risk of cardiovascular disease.

Compare Similar Items

Show Difference

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OriGene

50-167-8682

--


Antigen:
ESR2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q92731

Gene Symbols:
ESR2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-260 of human ESR2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1E12

Conjugate:
Unconjugated

Gene:
ESR2

Gene Alias:
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2100

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8684

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Antigen:
VEGFC

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P49767

Gene Symbols:
VEGFC

Immunogen:
Human recombit protein fragment corresponding to amino acids 112-227 of human VEGFC produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI4A1

Conjugate:
Unconjugated

Gene:
VEGFC

Gene Alias:
Flt4-L, LMPH1D, VRP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7424

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8685

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Antigen:
KRT5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P13647

Gene Symbols:
KRT5

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-273 of human KRT5 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4A7

Conjugate:
Unconjugated

Gene:
KRT5

Gene Alias:
CK5, DDD, DDD1, EBS2, K5, KRT5A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3852

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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OriGene

50-167-8686

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Antigen:
WFDC2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q14508

Gene Symbols:
WFDC2

Immunogen:
Human recombit protein fragment corresponding to amino acids 31-124 of human WFDC2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1G7

Conjugate:
Unconjugated

Gene:
WFDC2

Gene Alias:
EDDM4, HE4, WAP5, dJ461P17.6

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10406

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid