50-167-8875

TYMS Monoclonal Antibody (OTI5H8), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-8875-Each-of-1 In Stock ₹ 43,217.21

50-167-8875 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

TYMS

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P04818

Gene Symbols

TYMS

Immunogen

Full length human recombit protein of human TYMS produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI5H8

Conjugate

Unconjugated

Gene

TYMS

Gene Alias

HST422, TMS, TS

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7298

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Thymidylate Synthase (TS) (EC 2.1.1.45) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis
  • TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors
  • Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate
  • Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Compare Similar Items

Show Difference

Img

OriGene

50-167-8875

--


Antigen:
TYMS

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P04818

Gene Symbols:
TYMS

Immunogen:
Full length human recombit protein of human TYMS produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5H8

Conjugate:
Unconjugated

Gene:
TYMS

Gene Alias:
HST422, TMS, TS

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7298

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8876

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Antigen:
RASGRP3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8IV61

Gene Symbols:
RASGRP3

Immunogen:
Human recombit protein fragment corresponding to amino acids 380-690 of human RASGRP3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI3B9

Conjugate:
Unconjugated

Gene:
RASGRP3

Gene Alias:
GRP3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25780

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8877

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Antigen:
WWC1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8IX03

Gene Symbols:
WWC1

Immunogen:
Full length human recombit protein of human WWC1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI1H8

Conjugate:
Unconjugated

Gene:
WWC1

Gene Alias:
HBEBP3, HBEBP36, KIBRA, MEMRYQTL, PPP1R168

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23286

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8878

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Antigen:
WWC1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8IX03

Gene Symbols:
WWC1

Immunogen:
Full length human recombit protein of human WWC1 produced in HEK293T cell.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI1H8

Conjugate:
Unconjugated

Gene:
WWC1

Gene Alias:
HBEBP3, HBEBP36, KIBRA, MEMRYQTL, PPP1R168

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23286

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid