50-167-91

IL-4 Monoclonal Antibody (11B11), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-167-91-Each-of-1 In Stock ₹ 26,523.60

50-167-91 - Each of 1

₹ 26,523.60

In Stock

Quantity

1

Base Price: ₹ 26,523.60

GST (18%): ₹ 4,774.248

Total Price: ₹ 31,297.848

Antigen

IL-4

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P07750

Gene Symbols

Il4

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16189

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

11B11

Conjugate

Alexa Fluor 488

Gene

Il4

Gene Alias

B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

Description

  • Description: The 11B11 antibody reacts with mouse interleukin-4 (IL-4), a 14 kD cytokine
  • The 11B11 antibody is a neutralizing antibody
  • Mouse IL-4, also known as BCDF, BCGF-1 and BSF-1, is secreted by activated Th2 and natural killer T cells, and to a lesser extent by Th1 and mast cells
  • IL-4 is species-specific and promotes proliferation and differentiation of B cells
  • IL-4, in conjunction with other signals such as CD40, induces Ig isotype switching of B cells and the upregulation of surface MHC class II and CD23
  • Applications Reported: This 11B11 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This 11B11 antibody has been tested by intracellular staining and flow cytometric analysis of Th2 polarized and stimulated mouse splenocytes
  • This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor
  • IL-4 has been found to have the broadest range of actions
  • The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13
  • STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4
  • The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q
  • In particular, IL-4 is located in close proximity to IL13 on the chromosome
  • Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome
  • IL-4 delta 2 is a known splice variant of IL-4.

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Img

Fischer Scientific

50-167-91

--


Antigen:
IL-4

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P07750

Gene Symbols:
Il4

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16189

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
11B11

Conjugate:
Alexa Fluor 488

Gene:
Il4

Gene Alias:
B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

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OriGene

50-167-9101

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Antigen:
CDKN2A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8N726

Gene Symbols:
CDKN2A

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI5H8

Conjugate:
Unconjugated

Gene:
CDKN2A

Gene Alias:
ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-9102

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Antigen:
CD5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P06127

Gene Symbols:
CD5

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
921

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI8C10

Conjugate:
Unconjugated

Gene:
CD5

Gene Alias:
LEU1, T1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

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50-167-9103

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Antigen:
VSNL1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P62760

Gene Symbols:
VSNL1

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7447

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2D5

Conjugate:
Unconjugated

Gene:
VSNL1

Gene Alias:
HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b