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50-167-94

IL-10 Monoclonal Antibody (JES5-16E3), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-167-94-Each-of-1 In Stock ₹ 11,892.84

50-167-94 - Each of 1

₹ 11,892.84

In Stock

Quantity

1

Base Price: ₹ 11,892.84

GST (18%): ₹ 2,140.711

Total Price: ₹ 14,033.551

Antigen

IL-10

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P18893

Gene Symbols

IL10

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16153

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

JES5-16E3

Conjugate

Alexa Fluor 488

Gene

IL10

Gene Alias

CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Host Species

Rat

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b κ

Description

  • Description: The JES5-16E3 antibody reacts with mouse interleukin-10 (IL-10)
  • Mouse IL-10 is an ∽18 kDa factor also known as Cytokine Synthesis Inhibitory Factor (CSIF)
  • In the mouse, Th2 cells, B1 cells, macrophages, and keratinocytes are the major cell subsets that produce IL-10
  • IL-10 inhibits synthesis of Th1 cytokines and proliferation of T cells, and acts as a costimulatory signal for mast cells, developing thymocytes and the Th2 response
  • Applications Reported: The JES5-16E3 antibody has been reported for use in capture of mouse IL-10 by ELISA and ELISPOT, intracellular staining for flow cytometric analysis, IHC, and neutralization of IL-10 bioactivity
  • Applications Tested: The Alexa Fluor™ 488 conjugated JES5-16E3 antibody has been tested by intracellular immunofluorescent staining with flow cytometric analysis and can be used at less than or equal to 0.50 μg per million cells in 100 μL volume
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes
  • This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages
  • It also enhances B cell survival, proliferation, and antibody production
  • Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway
  • Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract
  • Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis
  • Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

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Show Difference

Img

Fischer Scientific

50-167-94

--

Antigen:
IL-10
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P18893
Gene Symbols:
IL10
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16153
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
JES5-16E3
Conjugate:
Alexa Fluor 488
Gene:
IL10
Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ

Img

OriGene

50-167-9400

--

Antigen:
OAS2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P29728
Gene Symbols:
OAS2
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4939
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI4B11
Conjugate:
Unconjugated
Gene:
OAS2
Gene Alias:
2′-5′-oligoadenylate synthetase 2
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1

Img

OriGene

50-167-9403

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Antigen:
FEN1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P39748
Gene Symbols:
FEN1
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2237
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI2B2
Conjugate:
Unconjugated
Gene:
FEN1
Gene Alias:
FEN-1, MF1, RAD2
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
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OriGene

50-167-9405

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Antigen:
B2M
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P61769
Gene Symbols:
B2M
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
567
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
__
Clone:
OTI1A9
Conjugate:
__
Gene:
B2M
Gene Alias:
IMD43
Host Species:
Mouse
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1