50-167-9537
BCL2 Monoclonal Antibody (OTI2E5), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-9537-Each-of-1 | In Stock | ₹ 43,217.21 |
50-167-9537 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
BCL2
Classification
Monoclonal
Conjugate
Unconjugated
Gene
BCL2
Gene Alias
Bcl-2, PPP1R50
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
596
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2E5
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P10415
Gene Symbols
BCL2
Immunogen
Full length human recombit protein of human BCL2 produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
- The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
- Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
- Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
- Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
- Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
- In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
- Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
- The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
Compare Similar Items
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Antigen: BCL2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: BCL2
Gene Alias: Bcl-2, PPP1R50
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 596
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2E5
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P10415
Gene Symbols: BCL2
Immunogen: Full length human recombit protein of human BCL2 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
BCL2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
BCL2
Gene Alias:
Bcl-2, PPP1R50
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
596
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2E5
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P10415
Gene Symbols:
BCL2
Immunogen:
Full length human recombit protein of human BCL2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: EZH2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: EZH2
Gene Alias: ENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2146
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI10B10
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q15910
Gene Symbols: EZH2
Immunogen: Human recombit protein fragment corresponding to amino acids 182-431 of human EZH2 ( NP_004447) produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
EZH2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
EZH2
Gene Alias:
ENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2146
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI10B10
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q15910
Gene Symbols:
EZH2
Immunogen:
Human recombit protein fragment corresponding to amino acids 182-431 of human EZH2 ( NP_004447) produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: CDCA7L
Classification: Monoclonal
Conjugate: Unconjugated
Gene: CDCA7L
Gene Alias: JPO2, R1, RAM2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55536
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI4A2
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q96GN5
Gene Symbols: CDCA7L
Immunogen: Human recombit protein fragment corresponding to amino acids 1-337 of human CDCA7L produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CDCA7L
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
CDCA7L
Gene Alias:
JPO2, R1, RAM2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55536
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI4A2
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q96GN5
Gene Symbols:
CDCA7L
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-337 of human CDCA7L produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: NAB1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: NAB1
Gene Alias: NGFI-A binding protein 1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4664
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI2H3
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q13506
Gene Symbols: NAB1
Immunogen: Human recombit protein fragment corresponding to amino acids 237-487 of human NAB1 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
NAB1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
NAB1
Gene Alias:
NGFI-A binding protein 1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4664
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI2H3
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q13506
Gene Symbols:
NAB1
Immunogen:
Human recombit protein fragment corresponding to amino acids 237-487 of human NAB1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1