50-167-9879

IRAK2 Monoclonal Antibody (OTI1D4), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-9879-Each-of-1 In Stock ₹ 43,217.21

50-167-9879 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

IRAK2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O43187

Gene Symbols

IRAK2

Immunogen

Human recombit protein fragment corresponding to amino acids 362-625 of human IRAK2 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI1D4

Conjugate

Unconjugated

Gene

IRAK2

Gene Alias

IRAK-2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3656

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • IRAK2 (interleukin-1 receptor-associated kinase-like 2) binds to the IL-1 type I receptor following IL-1 engagment and triggers intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization
  • The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP)
  • IL-1 receptor-associated kinase (IRAK) mediates activation of NF-kappa-B , which is a pivotal transcription factor mediating inflammatory and immune response
  • A novel member in the IRAK/Pelle family was recently identified and designated IRAK2
  • Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-kappa-B activation
  • IRAKs also associate with Toll-like receptor (TLR) and the domit negative mutants of IRAKs inhibit LPS-induced NF-kappa-B activation
  • Members in IRAK/Pelle family play a central role in IL-1R and TLR mediated inflammatory responses to cytokine IL-1 and LPS
  • IRAK2 is expressed in a variety of human tissues.

Compare Similar Items

Show Difference

Img

OriGene

50-167-9879

--


Antigen:
IRAK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O43187

Gene Symbols:
IRAK2

Immunogen:
Human recombit protein fragment corresponding to amino acids 362-625 of human IRAK2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1D4

Conjugate:
Unconjugated

Gene:
IRAK2

Gene Alias:
IRAK-2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3656

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-9881

--


Antigen:
GLI1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08151

Gene Symbols:
GLI1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-410 of human GLI1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2G1

Conjugate:
Unconjugated

Gene:
GLI1

Gene Alias:
GLI

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2735

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-9883

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Antigen:
VWF

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P04275

Gene Symbols:
VWF

Immunogen:
Human recombit protein fragment corresponding to amino acids 764-1263 of human VWF produced in SF9 cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI8F10

Conjugate:
Unconjugated

Gene:
VWF

Gene Alias:
F8VWF, VWD

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7450

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-9884

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Antigen:
LMNB2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q03252

Gene Symbols:
LMNB2

Immunogen:
Full length human recombit protein of human LMNB2 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2C6

Conjugate:
Unconjugated

Gene:
LMNB2

Gene Alias:
EPM9, LAMB2, LMN2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84823

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid