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50-168-0055

SETD2 Mouse anti-Human, Clone: OTI1C4, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-0055-Each-of-1 In Stock ₹ 43,217.21

50-168-0055 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

SETD2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q9BYW2

Gene Symbols

SETD2

Immunogen

Human recombit protein fragment corresponding to amino acids 1787-2144 of human SETD2 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI1C4

Conjugate

Unconjugated

Gene

SETD2

Gene Alias

HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, p231HBP

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29072

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Histone methyltransferase that specifically trimethylates ′Lys-36′ of histone H3 (H3K36me3) using dimethylated ′Lys-36′ (H3K36me2) as substrate
  • Represents the main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation
  • Plays a role in chromatin structure modulation during elongation by coordinating recruitment of the FACT complex and by interacting with hyperphosphorylated POLR2A
  • Acts as a key regulator of DNA mismatch repair in G1 and early S phase by generating H3K36me3, a mark required to recruit MSH6 subunit of the MutS alpha complex: early recruitment of the MutS alpha complex to chromatin to be replicated allows a quick identification of mismatch DNA to initiate the mismatch repair reaction
  • H3K36me3 also plays an essential role in the maintece of a heterochromatic state, by recruiting DNA methyltransferase DNMT3A
  • H3K36me3 is also enhanced in intron-containing genes, suggesting that SETD2 recruitment is enhanced by splicing and that splicing is coupled to recruitment of elongating RNA polymerase
  • Required during angiogenesis
  • Recruited to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression.

Compare Similar Items

Show Difference

Img

OriGene

50-168-0055

--

Antigen:
SETD2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9BYW2
Gene Symbols:
SETD2
Immunogen:
Human recombit protein fragment corresponding to amino acids 1787-2144 of human SETD2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI1C4
Conjugate:
Unconjugated
Gene:
SETD2
Gene Alias:
HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, p231HBP
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29072
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-0056

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Antigen:
NRBF2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q96F24
Gene Symbols:
NRBF2
Immunogen:
Full length human recombit protein of human NRBF2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Western Blot
Clone:
OTI1F3
Conjugate:
Unconjugated
Gene:
NRBF2
Gene Alias:
COPR, COPR1, COPR2, NRBF-2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29982
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

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OriGene

50-168-0058

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Antigen:
S100A9
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P06702
Gene Symbols:
S100A9
Immunogen:
Full length human recombit protein of human S100A9 produced in SF9 cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI3F8
Conjugate:
Unconjugated
Gene:
S100A9
Gene Alias:
60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6280
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

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OriGene

50-168-0059

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Antigen:
S100A9
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P06702
Gene Symbols:
S100A9
Immunogen:
Full length human recombit protein of human S100A9 produced in SF9 cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin)
Clone:
OTI7B1
Conjugate:
Unconjugated
Gene:
S100A9
Gene Alias:
60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6280
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid