50-168-0322

ERBB4 Monoclonal Antibody (OTI1H6), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-0322-Each-of-1 In Stock ₹ 43,217.21

50-168-0322 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

ERBB4

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ERBB4

Gene Alias

ALS19, HER4, p180erbB4

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2066

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

OTI1H6

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q15303

Gene Symbols

ERBB4

Immunogen

Human recombit protein fragment corresponding to amino acids 992-1308 of human ERBB4 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • ErbB 4 (Her-4, c-erbB-4, v-erbB-4) is a member of the class I receptor kinase family
  • With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes
  • The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains
  • ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases)
  • ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself
  • Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
  • ErbB 4 is most predomitly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum
  • Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361
  • Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
  • ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some maligcies.

Compare Similar Items

Show Difference

Img

OriGene

50-168-0322

--


Antigen:
ERBB4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
ALS19, HER4, p180erbB4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2066

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI1H6

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q15303

Gene Symbols:
ERBB4

Immunogen:
Human recombit protein fragment corresponding to amino acids 992-1308 of human ERBB4 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-0323

--


Antigen:
ERBB4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
ALS19, HER4, p180erbB4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2066

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI1D9

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q15303

Gene Symbols:
ERBB4

Immunogen:
Human recombit protein fragment corresponding to amino acids 992-1308 of human ERBB4 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-0325

--


Antigen:
LGALS3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
LGALS3

Gene Alias:
CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3958

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI4A7

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P17931

Gene Symbols:
LGALS3

Immunogen:
Full length human recombit protein of human LGALS3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-0326

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Antigen:
MDM2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MDM2

Gene Alias:
ACTFS, HDMX, hdm2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4193

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI2H4

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q00987

Gene Symbols:
MDM2

Immunogen:
Human recombit protein fragment corresponding to amino acids 119-438 of human MDM2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1