50-168-1256

JAK2 Monoclonal Antibody (OTI2F5), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1256-Each-of-1 In Stock ₹ 43,217.21

50-168-1256 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

JAK2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O60674

Gene Symbols

JAK2

Immunogen

Human recombit protein fragment corresponding to amino acids 297-596 of human JAK2 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI2F5

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

JTK10, THCYT3

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3717

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Janus Activating Kinase 2 (JAK2) is a non-rececptor tyrosine kinase involved in various processes such as cell growth, development, differentiation, and histone modifications
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting this gene can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

Show Difference

Img

OriGene

50-168-1256

--


Antigen:
JAK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
Human recombit protein fragment corresponding to amino acids 297-596 of human JAK2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2F5

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
JTK10, THCYT3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1259

--


Antigen:
CTGF

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P29279

Gene Symbols:
CTGF

Immunogen:
Human recombit protein fragment corresponding to amino acids 27-349 of human CTGF produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI2C9

Conjugate:
Unconjugated

Gene:
CTGF

Gene Alias:
CCN2, HCS24, IGFBP8, NOV2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1490

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1260

--


Antigen:
CTGF

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P29279

Gene Symbols:
CTGF

Immunogen:
Human recombit protein fragment corresponding to amino acids 27-349 of human CTGF produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI5C10

Conjugate:
Unconjugated

Gene:
CTGF

Gene Alias:
CCN2, HCS24, IGFBP8, NOV2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1490

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1261

--


Antigen:
CTGF

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P29279

Gene Symbols:
CTGF

Immunogen:
Human recombit protein fragment corresponding to amino acids 27-349 of human CTGF produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI2G3

Conjugate:
Unconjugated

Gene:
CTGF

Gene Alias:
CCN2, HCS24, IGFBP8, NOV2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1490

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid