50-168-1754

IL15 Mouse anti-Human, Clone: OTI2B4, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1754-Each-of-1 In Stock ₹ 43,217.21

50-168-1754 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

IL15

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P40933

Gene Symbols

IL15

Immunogen

Human recombit protein fragment corresponding to amino acids 49-162 of human IL15 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI2B4

Conjugate

Unconjugated

Gene

IL15

Gene Alias

IL-15

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3600

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • IL-15 (Interleukin 15 ) is a cytokine that regulates T and natural killer cell activation and proliferation
  • IL-15 and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other′s activity
  • The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2
  • IL-15 induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6
  • In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis
  • IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules
  • As such, IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases
  • Further, IL-15 is a widely expressed pro-inflammatory cytokine and has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases
  • Emerging data suggest that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes.

Compare Similar Items

Show Difference

Img

OriGene

50-168-1754

--


Antigen:
IL15

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P40933

Gene Symbols:
IL15

Immunogen:
Human recombit protein fragment corresponding to amino acids 49-162 of human IL15 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2B4

Conjugate:
Unconjugated

Gene:
IL15

Gene Alias:
IL-15

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3600

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1755

--


Antigen:
EIF4EBP3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O60516

Gene Symbols:
EIF4EBP3

Immunogen:
Full length human recombit protein of human EIF4EBP3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3B9

Conjugate:
Unconjugated

Gene:
EIF4EBP3

Gene Alias:
4E-BP3, 4EBP3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8637

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1756

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Antigen:
FGF13

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q92913

Gene Symbols:
FGF13

Immunogen:
Full length human recombit protein of human FGF13 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1D5

Conjugate:
Unconjugated

Gene:
FGF13

Gene Alias:
FGF-13, FGF2, FHF-2, FHF2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2258

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1757

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Antigen:
MDK

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P21741

Gene Symbols:
MDK

Immunogen:
Human recombit protein fragment corresponding to amino acids 21-143 of human MDK produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI8C6

Conjugate:
Unconjugated

Gene:
MDK

Gene Alias:
ARAP, MK, NEGF2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4192

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid