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50-168-1851

TNNI3 Monoclonal Antibody (OTI3B4), TrueMAB™, OriGene

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-168-1851-Each-of-1 In Stock ₹ 44,954.79

50-168-1851 - Each of 1

₹ 44,954.79

In Stock

Quantity

1

Base Price: ₹ 44,954.79

GST (18%): ₹ 8,091.862

Total Price: ₹ 53,046.652

Antigen

TNNI3

Classification

Monoclonal

Conjugate

Unconjugated

Gene

TNNI3

Gene Alias

CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7137

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

OTI3B4

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P19429

Gene Symbols

TNNI3

Immunogen

Recombit protein expressed in E.coli corresponding to amino acids 1-210 of human TNNI3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Cardiac Troponin I (Cardiac-specific troponin I, TnI, Troponin I) is an integral inhibitory protein in cardiac muscle that exists as part of a complex with troponin C (TnC) and troponin T (TnT)
  • The TnT subunit of troponin binds to tropomyosin-t form, a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments
  • Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, anabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement
  • The measurements of blood TnI and TnT levels is an important diagnostics indicator of heart muscle damage, and can be used to differentiate between angina and myocardial infarction in patients with chest pains
  • Cardiac Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro
  • Mutations in the Cardiac Troponin I gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Compare Similar Items

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Img

OriGene

50-168-1851

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Antigen:
TNNI3
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
TNNI3
Gene Alias:
CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7137
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI3B4
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P19429
Gene Symbols:
TNNI3
Immunogen:
Recombit protein expressed in E.coli corresponding to amino acids 1-210 of human TNNI3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b

Img

OriGene

50-168-1852

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Antigen:
SP110
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
SP110
Gene Alias:
IFI41, IFI75, IPR1, VODI
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3431
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2A1
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9HB58
Gene Symbols:
SP110
Immunogen:
Human recombit protein fragment corresponding to amino acids 232-521 of human SP110 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1

Img

OriGene

50-168-1854

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Antigen:
PDCD1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
PDCD1
Gene Alias:
CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5133
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI18H9
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q15116
Gene Symbols:
PDCD1
Immunogen:
Full length human recombit protein of human PDCD1 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1

Img

OriGene

50-168-1855

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Antigen:
JAG1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
JAG1
Gene Alias:
AGS, AGS1, AHD, AWS, CD339, HJ1, JAGL1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
182
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI3A10
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P78504
Gene Symbols:
JAG1
Immunogen:
Human recombit protein fragment corresponding to amino acids 523-759 of human JAG1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a