50-168-2002

MAVS Monoclonal Antibody (OTI8A11), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-2002-Each-of-1 In Stock ₹ 43,217.21

50-168-2002 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

MAVS

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q7Z434

Gene Symbols

MAVS

Immunogen

Human recombit protein fragment corresponding to amino acids 1-247 of human MAVS produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI8A11

Conjugate

Unconjugated

Gene

MAVS

Gene Alias

CARDIF, IPS-1, IPS1, VISA

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57506

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Two distinct signaling pathways activate the host innate immunity against viral infection
  • One pathway is reliant on members of the Toll-like receptor (TLR) family while the other uses the RNA helicase RIG-I as a receptor for intracellular viral double-stranded RNA as a trigger for the immune response
  • VISA is a mitochondrial membrane protein that was identified as a critical component in the IFN-b signaling pathways that recruits IRF-3 to RIG-I, leading to its activation and that of NF-kappa-B
  • VISA is also thought to interact with other components of the innate immune pathway such as the TLR adapter protein TRIF, TRAF2 and TRAF6
  • VISA also interacts with the IKK-a, IKK-b and IKK-iota kinases through its C-terminal region
  • Cleavage of this region by the Hepatitis C virus (HCV) protease allows HCV to escape the host immune system
  • At least three isoforms of VISA are known to exist.

Compare Similar Items

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Img

OriGene

50-168-2002

--


Antigen:
MAVS

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q7Z434

Gene Symbols:
MAVS

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-247 of human MAVS produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8A11

Conjugate:
Unconjugated

Gene:
MAVS

Gene Alias:
CARDIF, IPS-1, IPS1, VISA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57506

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2003

--


Antigen:
MAVS

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q7Z434

Gene Symbols:
MAVS

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-247 of human MAVS produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG3

Applications:
Western Blot

Clone:
OTI9C7

Conjugate:
Unconjugated

Gene:
MAVS

Gene Alias:
CARDIF, IPS-1, IPS1, VISA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57506

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2006

--


Antigen:
KRT16

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08779

Gene Symbols:
KRT16

Immunogen:
Full length human recombit protein of human KRT16 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2E6

Conjugate:
Unconjugated

Gene:
KRT16

Gene Alias:
CK16, FNEPPK, K16, K1CP, KRT16A, NEPPK, PC1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3868

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2009

--


Antigen:
ATP6V1C2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8NEY4

Gene Symbols:
ATP6V1C2

Immunogen:
Full length human recombit protein of human ATP6V1C2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI8C2

Conjugate:
Unconjugated

Gene:
ATP6V1C2

Gene Alias:
ATP6C2, VMA5

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
245973

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid