50-168-2317
ERBB2 Monoclonal Antibody (15C4-8), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-2317-Each-of-1 | In Stock | ₹ 43,217.21 |
50-168-2317 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
ERBB2
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P04626
Gene Symbols
ERBB2
Immunogen
HER2 extracellular domain (aa 23-652) expressed in HEK293 cells with a C-terminal DDK tag
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
15C4-8
Conjugate
Unconjugated
Gene
ERBB2
Gene Alias
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2064
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Description
- ErbB2 (Her2/neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR (epidermal growth factor receptor) family that regulates biological responses such as cell growth, differentiation, and tissue development
- ErbB2 has no ligand binding domain of its own and cannot bind growth factors
- However, ErbB2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase
- Autophosphorylation of tyrosine 1139 on ErbB2 allows binding of Grb2 and the Src SH2 domain, which allows activation of the Ras, Raf, ERK1/2 and JAK/STAT signaling pathways, respectively
- Alternative splicing of ErbB2 results in several transcript variants, some encoding different isoforms and others that have not been fully characterized
- In humans, the gene encoding ERBB2 is present on chromosome 17
- Amplification and/or overexpression of the ErbB2 gene has been reported in ovarian tumors, breast, lung and skin cancer.
Compare Similar Items
Show Difference
Antigen: ERBB2
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: HER2 extracellular domain (aa 23-652) expressed in HEK293 cells with a C-terminal DDK tag
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 15C4-8
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ERBB2
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
HER2 extracellular domain (aa 23-652) expressed in HEK293 cells with a C-terminal DDK tag
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
15C4-8
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ERBB2
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: HER2 extracellular domain (aa 23-652) expressed in HEK293 cells with a C-terminal DDK tag
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 λ
Applications: Flow Cytometry
Clone: 16C4-2
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ERBB2
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
HER2 extracellular domain (aa 23-652) expressed in HEK293 cells with a C-terminal DDK tag
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 λ
Applications:
Flow Cytometry
Clone:
16C4-2
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PARG
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q86W56
Gene Symbols: PARG
Immunogen: Human recombit protein fragment corresponding to amino acids 1-367 of human PARG produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI9F6
Conjugate: Unconjugated
Gene: PARG
Gene Alias: PARG99
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8505
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PARG
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q86W56
Gene Symbols:
PARG
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-367 of human PARG produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI9F6
Conjugate:
Unconjugated
Gene:
PARG
Gene Alias:
PARG99
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8505
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CABP4
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P57796
Gene Symbols: CABP4
Immunogen: Full length human recombit protein of human CABP4 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Western Blot
Clone: OTI9A7
Conjugate: Unconjugated
Gene: CABP4
Gene Alias: CRSD, CSNB2B
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 57010
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CABP4
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P57796
Gene Symbols:
CABP4
Immunogen:
Full length human recombit protein of human CABP4 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Western Blot
Clone:
OTI9A7
Conjugate:
Unconjugated
Gene:
CABP4
Gene Alias:
CRSD, CSNB2B
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
57010
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid