50-168-2343

LGR5 Monoclonal Antibody (OTI3F1), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-2343-Each-of-1 In Stock ₹ 43,217.21

50-168-2343 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

LGR5

Classification

Monoclonal

Conjugate

Unconjugated

Gene

LGR5

Gene Alias

FEX, GPR49, GPR67, GRP49, HG38

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14160, 8549

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry

Clone

OTI3F1

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O75473, Q9Z1P4

Gene Symbols

LGR5

Immunogen

Human recombit protein fragment corresponding to amino acids 22-543 of human LGR5 produced in HEK293 cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2a

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Description

  • G protein-coupled receptor GPR49 has been reported to be expressed in brain, skeletal muscle, placenta, and spinal cord
  • ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain libraries
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This ""turn-off"" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

Img

OriGene

50-168-2343

--


Antigen:
LGR5

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
LGR5

Gene Alias:
FEX, GPR49, GPR67, GRP49, HG38

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14160, 8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry

Clone:
OTI3F1

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O75473, Q9Z1P4

Gene Symbols:
LGR5

Immunogen:
Human recombit protein fragment corresponding to amino acids 22-543 of human LGR5 produced in HEK293 cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-2345

--


Antigen:
MAGEB3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MAGEB3

Gene Alias:
CT3.5

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4114

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5H8

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O15480

Gene Symbols:
MAGEB3

Immunogen:
Full length human recombit protein of human MAGEB3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-2347

--


Antigen:
LGR5

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
LGR5

Gene Alias:
FEX, GPR49, GPR67, GRP49, HG38

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14160, 8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry

Clone:
OTI7F2

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O75473, Q9Z1P4

Gene Symbols:
LGR5

Immunogen:
Human recombit protein fragment corresponding to amino acids 22-543 of human LGR5 produced in HEK293 cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-2348

--


Antigen:
MAGEB3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MAGEB3

Gene Alias:
CT3.5

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4114

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI1D3

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O15480

Gene Symbols:
MAGEB3

Immunogen:
Full length human recombit protein of human MAGEB3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1