50-168-2568

AR Monoclonal Antibody (OTI1D3), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-2568-Each-of-1 In Stock ₹ 43,217.21

50-168-2568 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

AR

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P10275

Gene Symbols

AR

Immunogen

Human recombit protein fragment corresponding to amino acids 420-659 of human AR produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1D3

Conjugate

Unconjugated

Gene

AR

Gene Alias

AIS, AR8, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

367

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors
  • The receptor is more than 90 kDa and has three major functional domains: the N-terminal domain, DNA-binding domain, and the androgen-binding domain
  • The androgen receptor is a ligand-activated transcription factor that binds active testosterone (T) and dihydrotestosterone (DHT)
  • Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes
  • The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis.AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain.Androgen Receptor is a phosphoprotein, and also regulates mitogen-activated protein kinase (MAP kinase)
  • The inhibition of the MEK1/2 pathway correlates directly with a change in phosphorylation state of the androgen receptor
  • Abnormalities in the AR signaling pathway have been linked to a number of diseases, including prostate cancer, Kennedy′s disease, and male infertility
  • Mutations in this gene are associated with complete androgen insensitivity (CAIS).

Compare Similar Items

Show Difference

Img

OriGene

50-168-2568

--


Antigen:
AR

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P10275

Gene Symbols:
AR

Immunogen:
Human recombit protein fragment corresponding to amino acids 420-659 of human AR produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1D3

Conjugate:
Unconjugated

Gene:
AR

Gene Alias:
AIS, AR8, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
367

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2569

--


Antigen:
ESR1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P03372

Gene Symbols:
ESR1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-310 of human ESR1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5E11

Conjugate:
Unconjugated

Gene:
ESR1

Gene Alias:
ER, ESR, ESRA, ESTRR, Era, NR3A1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2099, 403640

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2570

--


Antigen:
ESRRA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P11474

Gene Symbols:
ESRRA

Immunogen:
Human recombit protein fragment corresponding to amino acids 206-417 of human ESRRA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3G10

Conjugate:
Unconjugated

Gene:
ESRRA

Gene Alias:
ERR1, ERRa, ERRalpha, ESRL1, NR3B1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2101

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2572

--


Antigen:
SPANXN3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q5MJ09

Gene Symbols:
SPANXN3

Immunogen:
Full length human recombit protein of human SPANXN3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1B2

Conjugate:
Unconjugated

Gene:
SPANXN3

Gene Alias:
CT11.8, SPANX-N3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
139067

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid