50-168-2651

ERBB3 Monoclonal Antibody (OTI3C1), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-2651-Each-of-1 In Stock ₹ 43,217.21

50-168-2651 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

ERBB3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P21860

Gene Symbols

ERBB3

Immunogen

Human recombit protein fragment corresponding to amino acids 983-1342 of human ERBB3 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI3C1

Conjugate

Unconjugated

Gene

ERBB3

Gene Alias

ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2065

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
  • ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
  • Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
  • The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6.2kb mRNA which is translated into a 160/180kDa glycoprotein
  • The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
  • Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
  • Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
  • One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
  • Additional splice variants have also been reported, but they have not been thoroughly characterized.

Compare Similar Items

Show Difference

Img

OriGene

50-168-2651

--


Antigen:
ERBB3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P21860

Gene Symbols:
ERBB3

Immunogen:
Human recombit protein fragment corresponding to amino acids 983-1342 of human ERBB3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3C1

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2065

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2652

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Antigen:
CD34

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P28906

Gene Symbols:
CD34

Immunogen:
Human recombit protein fragment corresponding to amino acids 312-385 of human CD34 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI10C8

Conjugate:
Unconjugated

Gene:
CD34

Gene Alias:
CD34 molecule

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
947

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2659

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Antigen:
APBB1IP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q7Z5R6

Gene Symbols:
APBB1IP

Immunogen:
Full length human recombit protein of human APBB1IP produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3F12

Conjugate:
Unconjugated

Gene:
APBB1IP

Gene Alias:
INAG1, PREL1, RARP1, RIAM

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54518

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Biolegend

50-168-266

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