50-168-2846

NEDD9 Monoclonal Antibody (OTI3H4), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-2846-Each-of-1 In Stock ₹ 43,217.21

50-168-2846 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

NEDD9

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q14511

Gene Symbols

NEDD9

Immunogen

Full length human recombit protein of human NEDD9 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI3H4

Conjugate

Unconjugated

Gene

NEDD9

Gene Alias

CAS-L, CAS2, CASL, CASS2, HEF1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4739

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • HEF-1 is a multifunctional protein involved in integrin-based signaling that affects cell motility, growth, apoptosis and oncogenic transformation
  • The Cas family of docking proteins have been the subject of intense research because of their role in cell motility, growth, apoptosis and oncogenic transformation
  • These proteins are substrates of focal adhesion kinase (FAK) and the Src family of tyrosine kinases two active targets for drug development
  • HEF1 protein production increases levels of mRNA transcripts that encode proteins associated with motility, cell transformation and invasiveness, including several metalloproteinases, MLCK, p160ROCK and ErbBi
  • HEF1 overproduction also mediates apoptosis in epithelial-derived cell lines, including MCF7 and HeLa cells
  • Recent clinical studies at another institution have found that overexpression of BCAR1 (p130Cas), a related protein, is associated with tamoxifen resistance
  • This highlights the importance of studying the role of this family of proteins in cancer prognosis.

Compare Similar Items

Show Difference

Img

OriGene

50-168-2846

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Antigen:
NEDD9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q14511

Gene Symbols:
NEDD9

Immunogen:
Full length human recombit protein of human NEDD9 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3H4

Conjugate:
Unconjugated

Gene:
NEDD9

Gene Alias:
CAS-L, CAS2, CASL, CASS2, HEF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4739

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2847

--


Antigen:
ZCCHC17

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9NP64

Gene Symbols:
ZCCHC17

Immunogen:
Full length human recombit protein of human ZCCHC17 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI1F11

Conjugate:
Unconjugated

Gene:
ZCCHC17

Gene Alias:
HSPC251, PS1D, pNO40

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51538

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2848

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Antigen:
WDR92

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q96MX6

Gene Symbols:
WDR92

Immunogen:
Full length human recombit protein of human WDR92 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI4B5

Conjugate:
Unconjugated

Gene:
WDR92

Gene Alias:
WD repeat domain 92

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116143

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Biolegend

50-168-285

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