50-168-3017
TINF2 Mouse anti-Human, Mouse, Rat, Clone: OTI2C12, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-3017-Each-of-1 | In Stock | ₹ 43,217.21 |
50-168-3017 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
TINF2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q9BSI4, Q9QXG9
Gene Symbols
Tinf2
Immunogen
Human recombit protein fragment corresponding to amino acids 266-347 of human TINF2 produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2b
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2C12
Conjugate
Unconjugated
Gene
TINF2
Gene Alias
DKCA3, TIN2
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26277, 28113, 290232
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- TRF1 is a negative regulator of telomere length maintece (3)
- Recently two proteins, tankyrase and Tin2, which bind to mammalian TRF1, have been identified
- Tankyrase is a protein with homology to ankyrins as well as to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP) (3)
- Tankyrase localizes to telomeres by binding to the telomeric repeat binding factor 1 (TRF1) through its ankyrin repeats (2,3)
- Tankyrase exhibits PARP activity functioning as acceptors for adenosine diphosphate (ADP)-ribosylation
- Since ADP-ribosylation of TRF1 diminishes its ability to bind to telomeric DNA, this suggests that telomere function in human cells is regulated by poly (ADP)-ribosylation
- Both the cell cycle and TRF1 may regulate the subcellular localization of tankyrase
- The cDNA coding for TIN2 protein was isolated as interacting partner of TRF1 from a yeast two-hybrid cDNA library screening (1)
- Tin2 localizes to telomeres and is essential for proper regulation of telomere length
- TIN2, like TRF1, is widely and constitutively expressed, suggesting that these proteins act together to counterbalance telomere elongation by telomerase
- However, endogenous TIN2, like endogenousTRF1, is not highly expressed, and therefore may be difficult to visualize by immunostaining in certain cell systems.
Compare Similar Items
Show Difference
Antigen: TINF2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q9BSI4, Q9QXG9
Gene Symbols: Tinf2
Immunogen: Human recombit protein fragment corresponding to amino acids 266-347 of human TINF2 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2C12
Conjugate: Unconjugated
Gene: TINF2
Gene Alias: DKCA3, TIN2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26277, 28113, 290232
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TINF2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9BSI4, Q9QXG9
Gene Symbols:
Tinf2
Immunogen:
Human recombit protein fragment corresponding to amino acids 266-347 of human TINF2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2C12
Conjugate:
Unconjugated
Gene:
TINF2
Gene Alias:
DKCA3, TIN2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26277, 28113, 290232
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: AGR2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O95994
Gene Symbols: AGR2
Immunogen: Human recombit protein fragment corresponding to amino acids 21-175 of human AGR2 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2B10
Conjugate: Unconjugated
Gene: AGR2
Gene Alias: AG-2, AG2, GOB-4, HAG-2, HEL-S-116, HPC8, PDIA17, XAG-2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10551
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
AGR2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O95994
Gene Symbols:
AGR2
Immunogen:
Human recombit protein fragment corresponding to amino acids 21-175 of human AGR2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2B10
Conjugate:
Unconjugated
Gene:
AGR2
Gene Alias:
AG-2, AG2, GOB-4, HAG-2, HEL-S-116, HPC8, PDIA17, XAG-2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10551
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: AGR2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O95994
Gene Symbols: AGR2
Immunogen: Human recombit protein fragment corresponding to amino acids 21-175 of human AGR2 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1H8
Conjugate: Unconjugated
Gene: AGR2
Gene Alias: AG-2, AG2, GOB-4, HAG-2, HEL-S-116, HPC8, PDIA17, XAG-2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10551
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
AGR2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O95994
Gene Symbols:
AGR2
Immunogen:
Human recombit protein fragment corresponding to amino acids 21-175 of human AGR2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1H8
Conjugate:
Unconjugated
Gene:
AGR2
Gene Alias:
AG-2, AG2, GOB-4, HAG-2, HEL-S-116, HPC8, PDIA17, XAG-2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10551
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SMC1A
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q14683, Q9CU62
Gene Symbols: SMC1A
Immunogen: Human recombit protein fragment corresponding to amino acids 889-1016 of human SMC1A produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI11E1
Conjugate: Unconjugated
Gene: SMC1A
Gene Alias: CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 24061, 8243
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SMC1A
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q14683, Q9CU62
Gene Symbols:
SMC1A
Immunogen:
Human recombit protein fragment corresponding to amino acids 889-1016 of human SMC1A produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI11E1
Conjugate:
Unconjugated
Gene:
SMC1A
Gene Alias:
CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
24061, 8243
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid