50-168-3181

VTCN1 Mouse anti-Human, Clone: OTI9E9, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-3181-Each-of-1 In Stock ₹ 43,217.21

50-168-3181 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

VTCN1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q7Z7D3

Gene Symbols

VTCN1

Immunogen

Human recombit protein fragment corresponding to amino acids 31-117 of human VTCN1 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Western Blot

Clone

OTI9E9

Conjugate

Unconjugated

Gene

VTCN1

Gene Alias

B7-H4, B7H4, B7S1, B7X, B7h.5, PRO1291, VCTN1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

79679

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • B7-H4 (B7x, VTCN1) a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity
  • Although B7-H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production
  • B7-H4 deficient mice are only minimally affected; suggesting B7-H4 is important in the fine tuning of the T-cell mediated immune response
  • B7-H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells
  • Aberrant expression has been associated with cancers of the lung, breast and ovary in humans
  • B7-H4 is expressed primarily on the membrane of lymphoid cells, and as an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, it is involved in mediating cellular and humoral immune responses
  • Overexpression of B7-H4 is associated with certain maligcies, including ovarian and breast cancer, which may be a mechanism by which tumor cells suppress T cell immunity and facilitate tumor progression
  • Further, VTCN1 may be a useful biomarker for the early detection of ovarian cancer and Renal Cell Carcinoma (RCC).

Compare Similar Items

Show Difference

Img

OriGene

50-168-3181

--


Antigen:
VTCN1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q7Z7D3

Gene Symbols:
VTCN1

Immunogen:
Human recombit protein fragment corresponding to amino acids 31-117 of human VTCN1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI9E9

Conjugate:
Unconjugated

Gene:
VTCN1

Gene Alias:
B7-H4, B7H4, B7S1, B7X, B7h.5, PRO1291, VCTN1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79679

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3183

--


Antigen:
UROD

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P06132

Gene Symbols:
UROD

Immunogen:
Full length human recombit protein of human UROD produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI2G7

Conjugate:
Unconjugated

Gene:
UROD

Gene Alias:
PCT, UPD

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7389

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3184

--


Antigen:
ELF4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q99607

Gene Symbols:
ELF4

Immunogen:
Human recombit protein fragment corresponding to amino acids 83-345 of human ELF4 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2D8

Conjugate:
Unconjugated

Gene:
ELF4

Gene Alias:
ELFR, MEF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2000

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3185

--


Antigen:
ELF4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q99607

Gene Symbols:
ELF4

Immunogen:
Human recombit protein fragment corresponding to amino acids 83-345 of human ELF4 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1E4

Conjugate:
Unconjugated

Gene:
ELF4

Gene Alias:
ELFR, MEF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2000

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid