50-168-3597
FOXO1 Monoclonal Antibody (OTI2C6), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-3597-Each-of-1 | In Stock | ₹ 43,217.21 |
50-168-3597 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
FOXO1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q12778
Gene Symbols
FOXO1
Immunogen
Human recombit protein fragment corresponding to amino acids 356-655 of human FOXO1 produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
OTI2C6
Conjugate
Unconjugated
Gene
FOXO1
Gene Alias
FKH1, FKHR, FOXO1A
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2308
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- FOXO1 (FKHR, ForKHead Box 01) is a member in a subfamily of the forkhead homeotic gene family of transcription factors
- Recent experiments have shown that FOXO1 can act as either a coactivator or a corepressor of nuclear receptor activity that is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein
- Association of FOXO1 with PAX3 has been implicated in alveolar rhabdomyosarcoma
- Recent studies link the anti-tumor activity of FOXO1, the process of autophagy and myogenic growth and differentiation
- FOXO1 is the main target of insulin signaling that regulated the metabolic homeostasis in response to oxidative stress
- FOXO1 binds to the insulin response element (IRE) with consensus sequence 5′-TT[G/A]TTTTG-3′ and the related Daf-16 family binding element (DBE) with consensus sequence 5′- TT[G/A]TTTAC-3′
- FOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass
- Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP
- In hepatocytes, FOXO1 promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1
- FOXO1 is an important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1.
Compare Similar Items
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Antigen: FOXO1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q12778
Gene Symbols: FOXO1
Immunogen: Human recombit protein fragment corresponding to amino acids 356-655 of human FOXO1 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI2C6
Conjugate: Unconjugated
Gene: FOXO1
Gene Alias: FKH1, FKHR, FOXO1A
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2308
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
FOXO1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q12778
Gene Symbols:
FOXO1
Immunogen:
Human recombit protein fragment corresponding to amino acids 356-655 of human FOXO1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI2C6
Conjugate:
Unconjugated
Gene:
FOXO1
Gene Alias:
FKH1, FKHR, FOXO1A
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2308
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: DDB2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q92466
Gene Symbols: DDB2
Immunogen: Human recombit protein fragment corresponding to amino acids 1-250 of human DDB2 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI2E12
Conjugate: Unconjugated
Gene: DDB2
Gene Alias: DDBB, UV-DDB2, XPE
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1643
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
DDB2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q92466
Gene Symbols:
DDB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-250 of human DDB2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI2E12
Conjugate:
Unconjugated
Gene:
DDB2
Gene Alias:
DDBB, UV-DDB2, XPE
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1643
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NFKBIE
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O00221
Gene Symbols: NFKBIE
Immunogen: Full length human recombit protein of human NFKBIE produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI6H8
Conjugate: Unconjugated
Gene: NFKBIE
Gene Alias: IKBE
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4794
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NFKBIE
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O00221
Gene Symbols:
NFKBIE
Immunogen:
Full length human recombit protein of human NFKBIE produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI6H8
Conjugate:
Unconjugated
Gene:
NFKBIE
Gene Alias:
IKBE
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4794
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: BEGAIN
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q9BUH8
Gene Symbols: BEGAIN
Immunogen: Human recombit protein fragment corresponding to amino acids 374-517 of human BEGAIN produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI4E8
Conjugate: Unconjugated
Gene: BEGAIN
Gene Alias: brain enriched guanylate kinase associated
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 57596
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BEGAIN
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9BUH8
Gene Symbols:
BEGAIN
Immunogen:
Human recombit protein fragment corresponding to amino acids 374-517 of human BEGAIN produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI4E8
Conjugate:
Unconjugated
Gene:
BEGAIN
Gene Alias:
brain enriched guanylate kinase associated
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
57596
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid