50-168-3791

NCK2 Monoclonal Antibody (OTI4H7), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-3791-Each-of-1 In Stock ₹ 43,217.21

50-168-3791 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

NCK2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O43639

Gene Symbols

NCK2

Immunogen

Full length human recombit protein of human NCK2 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Western Blot

Clone

OTI4H7

Conjugate

Unconjugated

Gene

NCK2

Gene Alias

GRB4, NCKbeta

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8440

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • NCK1 is one of the adaptor proteins which mediate specific protein-protein interactions in signaling processes
  • Adaptor proteins usually contain several domains like SH2 (Src homology 2) and SH3 which allow specific interactions with other specific proteins
  • NCK1 and NCK2 showing high sequence identity (68%) have three SH3 domains and a C-terminal SH2 domain
  • Both of them bind receptor tyrosine kinases such as PDGFR and other tyrosine phosphorylated proteins via their SH2 domains
  • Various molecules which interact with SH domains of Nck and regulate signaling process of actin cytoskeleton reorganization have been identified
  • Ncks are thought to have important functions in the development of mesodermal structures during embryogenesis, linked to a role in cell movement and cytoskeletal reorganization
  • Nck also have a function in modulating mRNA translation at the level of initiation by interacting eukayotic initiation factor 2 (eIF2)
  • Under the stressed conditions, protein synthesis is reduced by inhibiting the activity of eIF2 through the phosphorylation, transiently inhibiting recycling of eIF2 into its active form.

Compare Similar Items

Show Difference

Img

OriGene

50-168-3791

--


Antigen:
NCK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O43639

Gene Symbols:
NCK2

Immunogen:
Full length human recombit protein of human NCK2 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI4H7

Conjugate:
Unconjugated

Gene:
NCK2

Gene Alias:
GRB4, NCKbeta

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8440

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3793

--


Antigen:
RAX

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9Y2V3

Gene Symbols:
RAX

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-222 of human RAX produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI6C2

Conjugate:
Unconjugated

Gene:
RAX

Gene Alias:
MCOP3, RX

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
30062

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3794

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Antigen:
DNAJC27

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9NZQ0

Gene Symbols:
DNAJC27

Immunogen:
Full length human recombit protein of human DNAJC27 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI8A10

Conjugate:
Unconjugated

Gene:
DNAJC27

Gene Alias:
RBJ, RabJS

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51277

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3795

--


Antigen:
DNAJC27

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9NZQ0

Gene Symbols:
DNAJC27

Immunogen:
Full length human recombit protein of human DNAJC27 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI9H3

Conjugate:
Unconjugated

Gene:
DNAJC27

Gene Alias:
RBJ, RabJS

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51277

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid