50-168-4115

EGF Monoclonal Antibody (OTI8E2), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4115-Each-of-1 In Stock ₹ 43,217.21

50-168-4115 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

EGF

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P01133

Gene Symbols

EGF

Immunogen

Human recombit protein fragment corresponding to amino acids 1054-1207 of human EGF produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI8E2

Conjugate

Unconjugated

Gene

EGF

Gene Alias

HOMG4, URG

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1950

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • EGF (Epidermal growth factor) exerts its actions by binding to the EGF Receptor, a 170 kDa protein kinase
  • Activation of EGFR initiates diverse cellular pathways in response to toxic environmental stimuli, or to EGF binding to the receptor, the EGFR forms homo- or heterodimers with other family members
  • Each dimeric receptor complex initiates a distinct signaling pathway by recruiting different Src homology 2 (SH2) containing effector proteins
  • EGF is far and wide expressed in kidney, cerebrum, prostrate and salivary glands
  • EGF acts as a potent mitogenic factor and the phosphorylated receptor recruits adapter proteins like GRB2 that activates complex downstream signaling cascades
  • EGF activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STAT modules
  • Research studies suggest the protein may also play important role in activating the NF-kappa-B signaling cascade
  • Defects in the EGGF gene are the cause of hypomagnesemia type 4 and dysregulation has been associated with the growth and progression of certain cancers.

Compare Similar Items

Show Difference

Img

OriGene

50-168-4115

--


Antigen:
EGF

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P01133

Gene Symbols:
EGF

Immunogen:
Human recombit protein fragment corresponding to amino acids 1054-1207 of human EGF produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI8E2

Conjugate:
Unconjugated

Gene:
EGF

Gene Alias:
HOMG4, URG

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1950

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4117

--


Antigen:
PLAC8L1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
A1L4L8

Gene Symbols:
PLAC8L1

Immunogen:
Full length human recombit protein of human PLAC8L1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI8H8

Conjugate:
Unconjugated

Gene:
PLAC8L1

Gene Alias:
PLAC8 like 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
153770

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4118

--


Antigen:
DTWD1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8N5C7

Gene Symbols:
DTWD1

Immunogen:
Full length human recombit protein of human DTWD1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI2C2

Conjugate:
Unconjugated

Gene:
DTWD1

Gene Alias:
MDS009

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56986

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4119

--


Antigen:
DTWD1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8N5C7

Gene Symbols:
DTWD1

Immunogen:
Full length human recombit protein of human DTWD1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI2D2

Conjugate:
Unconjugated

Gene:
DTWD1

Gene Alias:
MDS009

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56986

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid