50-168-4121

RGMA Monoclonal Antibody (OTI1C5), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4121-Each-of-1 In Stock ₹ 43,217.21

50-168-4121 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

RGMA

Classification

Monoclonal

Conjugate

Unconjugated

Gene

RGMA

Gene Alias

RGM

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56963

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

OTI1C5

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q96B86

Gene Symbols

RGMA

Immunogen

Human recombit protein fragment corresponding to amino acids 169-424 of human RGMA produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system
  • Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses
  • Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition
  • Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway
  • It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.

Compare Similar Items

Show Difference

Img

OriGene

50-168-4121

--


Antigen:
RGMA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RGMA

Gene Alias:
RGM

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56963

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI1C5

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q96B86

Gene Symbols:
RGMA

Immunogen:
Human recombit protein fragment corresponding to amino acids 169-424 of human RGMA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-4124

--


Antigen:
DTWD1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
DTWD1

Gene Alias:
MDS009

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56986

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1D2

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8N5C7

Gene Symbols:
DTWD1

Immunogen:
Full length human recombit protein of human DTWD1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-4125

--


Antigen:
HOXA3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
HOXA3

Gene Alias:
HOX1, HOX1E

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3200

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI1C8

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O43365

Gene Symbols:
HOXA3

Immunogen:
Human recombit protein fragment corresponding to amino acids 40-276 of human HOXA3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-4127

--


Antigen:
ZFP57

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ZFP57

Gene Alias:
C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22715, 346171

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1E2

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8C6P8, Q9NU63

Gene Symbols:
ZFP57

Immunogen:
Full length human recombit protein of human ZFP57 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1