50-168-4209

CR1 Monoclonal Antibody (OTI2A8), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4209-Each-of-1 In Stock ₹ 43,217.21

50-168-4209 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

CR1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CR1

Gene Alias

C3BR, C4BR, CD35, KN

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1378

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2A8

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P17927

Gene Symbols

CR1

Immunogen

Human recombit protein fragment corresponding to amino acids 1900-2039 of human CR1 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • CD35 (CR1, Complement Receptor 1) is a cell membrane-bound, monomeric glycoprotein and its primary function is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules
  • CD35 protein mediates cellular binding to particles and immune complexes that have activated complement
  • The CD35 complex is four different allotypes (C,A,B,D) C is 160 kDa; A is 190 kDa; B is 220 kDa and D is 250 kDa
  • CD35 is involved in the processing of immune complexes, promoting of binding and phagocytosis of C3b complexes and inhibition of complement activation
  • CD35 is on neutrophils, eosinophils, monocytes, B-cells, some NK-cells, erythrocytes, myeloid leukemias, follicular dendritic reticulum cells and is negative on basophils
  • Decreases in expression of CD35 protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis
  • Mutations in the CD35 gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria
  • Alternate allele-specific splice variants encoding different isoforms of CD35 have been characterized
  • An additional secreted form of CD35 have also been described but has not been fully characterized.

Compare Similar Items

Show Difference

Img

OriGene

50-168-4209

--


Antigen:
CR1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CR1

Gene Alias:
C3BR, C4BR, CD35, KN

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1378

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2A8

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P17927

Gene Symbols:
CR1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1900-2039 of human CR1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-4210

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Antigen:
IL34

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IL34

Gene Alias:
C16orf77, IL-34

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
146433

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI4A6

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q6ZMJ4

Gene Symbols:
IL34

Immunogen:
Human recombit protein fragment corresponding to amino acids 77-242 of human IL34 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-4211

--


Antigen:
IL34

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IL34

Gene Alias:
C16orf77, IL-34

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
146433

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8C4

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q6ZMJ4

Gene Symbols:
IL34

Immunogen:
Human recombit protein fragment corresponding to amino acids 77-242 of human IL34 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-4213

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Antigen:
F10

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
F10

Gene Alias:
FX, FXA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2159

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI1B8

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P00742

Gene Symbols:
F10

Immunogen:
Human recombit protein fragment corresponding to amino acids 41-488 of human F10 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1