50-168-4243
TNFSF10 Monoclonal Antibody (OTI12E12), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-4243-Each-of-1 | In Stock | ₹ 44,954.79 |
50-168-4243 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,954.79
GST (18%): ₹ 8,091.862
Total Price: ₹ 53,046.652
Antigen
TNFSF10
Classification
Monoclonal
Conjugate
Unconjugated
Gene
TNFSF10
Gene Alias
APO2L, Apo-2L, CD253, TL2, TNLG6A, TRAIL
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8743
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Clone
OTI12E12
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P50591
Gene Symbols
TNFSF10
Immunogen
Human recombit protein fragment corresponding to amino acids 39-281 of human TNFSF10 produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family
- TRAIL preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues
- TRAIL binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG
- The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis
- The binding of TRAIL protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3
- Receptors for TRAIL include two death domain containing receptors, death receptor 4 (DR4) and DR5, as well as two decoy receptors, DcR1 and DcR2, lacking the intracellular signaling death domain
- TRAIL is a type II membrane protein and expressed in a variety of human tissues
- Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.
Compare Similar Items
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Antigen: TNFSF10
Classification: Monoclonal
Conjugate: Unconjugated
Gene: TNFSF10
Gene Alias: APO2L, Apo-2L, CD253, TL2, TNLG6A, TRAIL
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8743
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI12E12
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P50591
Gene Symbols: TNFSF10
Immunogen: Human recombit protein fragment corresponding to amino acids 39-281 of human TNFSF10 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
TNFSF10
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
TNFSF10
Gene Alias:
APO2L, Apo-2L, CD253, TL2, TNLG6A, TRAIL
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8743
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI12E12
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P50591
Gene Symbols:
TNFSF10
Immunogen:
Human recombit protein fragment corresponding to amino acids 39-281 of human TNFSF10 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: IDE
Classification: Monoclonal
Conjugate: Unconjugated
Gene: IDE
Gene Alias: INSULYSIN
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 25700, 3416
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI4E5
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P14735, P35559
Gene Symbols: IDE
Immunogen: Human recombit protein fragment corresponding to amino acids 800-1019 of human IDE produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG2b
Antigen:
IDE
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
IDE
Gene Alias:
INSULYSIN
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
25700, 3416
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI4E5
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P14735, P35559
Gene Symbols:
IDE
Immunogen:
Human recombit protein fragment corresponding to amino acids 800-1019 of human IDE produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG2b
Antigen: ABTB1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: ABTB1
Gene Alias: BPOZ, BTB3, BTBD21, EF1ABP, PP2259
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 80325
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI3G8
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q969K4
Gene Symbols: ABTB1
Immunogen: Full length human recombit protein of human ABTB1 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
ABTB1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ABTB1
Gene Alias:
BPOZ, BTB3, BTBD21, EF1ABP, PP2259
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
80325
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI3G8
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q969K4
Gene Symbols:
ABTB1
Immunogen:
Full length human recombit protein of human ABTB1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: EIF4E3
Classification: Monoclonal
Conjugate: Unconjugated
Gene: EIF4E3
Gene Alias: eIF-4E3, eIF4E-3
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 297481, 317649
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI2B9
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q8N5X7
Gene Symbols: EIF4E3
Immunogen: Full length human recombit protein of human EIF4E3 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
EIF4E3
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
EIF4E3
Gene Alias:
eIF-4E3, eIF4E-3
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
297481, 317649
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI2B9
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q8N5X7
Gene Symbols:
EIF4E3
Immunogen:
Full length human recombit protein of human EIF4E3 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1