50-168-4435

HLA Monoclonal Antibody (OTI4G7), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4435-Each-of-1 In Stock ₹ 43,217.21

50-168-4435 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

HLA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q30154

Gene Symbols

HLA-DRB5

Immunogen

Human recombit protein fragment corresponding to amino acids 30-266 of human HLA-DRB5 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI4G7

Conjugate

Unconjugated

Gene

HLA-DRB5

Gene Alias

major histocompatibility complex, class II, DR beta 5

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3127

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • HLA-DRB5 belongs to the HLA class II beta chain paralogues
  • This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane
  • It plays a central role in the immune system by presenting peptides derived from extracellular proteins
  • Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
  • The beta chain is approximately 26-28 kDa and its gene contains 6 exons
  • Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail
  • Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
  • Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5
  • The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted
  • There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Compare Similar Items

Show Difference

Img

OriGene

50-168-4435

--


Antigen:
HLA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q30154

Gene Symbols:
HLA-DRB5

Immunogen:
Human recombit protein fragment corresponding to amino acids 30-266 of human HLA-DRB5 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4G7

Conjugate:
Unconjugated

Gene:
HLA-DRB5

Gene Alias:
major histocompatibility complex, class II, DR beta 5

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3127

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4439

--


Antigen:
AZGP1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P25311

Gene Symbols:
AZGP1

Immunogen:
Human recombit protein fragment corresponding to amino acids 21-298 of human AZGP1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI10F2

Conjugate:
Unconjugated

Gene:
AZGP1

Gene Alias:
ZA2G, ZAG

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
563

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4442

--


Antigen:
BST1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q10588

Gene Symbols:
BST1

Immunogen:
Human recombit protein fragment corresponding to amino acids 29-318 of human BST1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI4E4

Conjugate:
Unconjugated

Gene:
BST1

Gene Alias:
CD157

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
683

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4444

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Antigen:
NUMBL

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9Y6R0

Gene Symbols:
NUMBL

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-225 of human NUMBL produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI6H7

Conjugate:
Unconjugated

Gene:
NUMBL

Gene Alias:
CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9253

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid