50-168-4450

CIITA Monoclonal Antibody (OTI7B12), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4450-Each-of-1 In Stock ₹ 43,217.21

50-168-4450 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

CIITA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P33076

Gene Symbols

CIITA

Immunogen

Human recombit protein fragment corresponding to amino acids 414-724 of human CIITA produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI7B12

Conjugate

Unconjugated

Gene

CIITA

Gene Alias

C2TA, CIITAIV, MHC2TA, NLRA

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4261

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CIITA contains an acidic transcriptional activation domain, four LRRs (leucine-rich repeats) and a GTP binding domain
  • It is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the "master control factor" for the expression of these genes
  • CIITA also binds GTP and uses GTP binding to facilitate its own transport into the nucleus
  • Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion
  • Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction.

Compare Similar Items

Show Difference

Img

OriGene

50-168-4450

--


Antigen:
CIITA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P33076

Gene Symbols:
CIITA

Immunogen:
Human recombit protein fragment corresponding to amino acids 414-724 of human CIITA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI7B12

Conjugate:
Unconjugated

Gene:
CIITA

Gene Alias:
C2TA, CIITAIV, MHC2TA, NLRA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4261

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4451

--


Antigen:
NUMBL

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9Y6R0

Gene Symbols:
NUMBL

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-225 of human NUMBL produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI8D2

Conjugate:
Unconjugated

Gene:
NUMBL

Gene Alias:
CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9253

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4452

--


Antigen:
ZBTB32

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9Y2Y4

Gene Symbols:
ZBTB32

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-300 of human ZBTB32 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI2H8

Conjugate:
Unconjugated

Gene:
ZBTB32

Gene Alias:
FAXF, FAZF, Rog, TZFP, ZNF538

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27033

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4453

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Antigen:
TERF1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P54274

Gene Symbols:
TERF1

Immunogen:
Full length human recombit protein of human TERF1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI3A1

Conjugate:
Unconjugated

Gene:
TERF1

Gene Alias:
PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7013

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid