50-168-4633
NEDD4 Monoclonal Antibody (OTI6E12), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-4633-Each-of-1 | In Stock | ₹ 44,954.79 |
50-168-4633 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,954.79
GST (18%): ₹ 8,091.862
Total Price: ₹ 53,046.652
Antigen
NEDD4
Classification
Monoclonal
Conjugate
Unconjugated
Gene
NEDD4
Gene Alias
NEDD4-1, RPF1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4734
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Clone
OTI6E12
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P46934
Gene Symbols
NEDD4
Immunogen
Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Description
- The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein
- It contains one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains
- It is involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity
- It acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53
- It is also reported to be involved in the budding of many viruses and is the regulator of epithelial Na+ channels, which lead to arterial hypertension
- NEDD4 protein is localized to the sarcolemmal region of muscle fibers
- Increase in NEDD4 protein expression leads to unloaded and denervated muscles as well as a decrease in Notch1 expression
- Hence it acts as down regulator of Notch-1 gene expression.
Compare Similar Items
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Antigen: NEDD4
Classification: Monoclonal
Conjugate: Unconjugated
Gene: NEDD4
Gene Alias: NEDD4-1, RPF1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4734
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI6E12
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P46934
Gene Symbols: NEDD4
Immunogen: Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
NEDD4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
NEDD4
Gene Alias:
NEDD4-1, RPF1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4734
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI6E12
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P46934
Gene Symbols:
NEDD4
Immunogen:
Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: NEDD4
Classification: Monoclonal
Conjugate: Unconjugated
Gene: NEDD4
Gene Alias: NEDD4-1, RPF1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4734
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI7A1
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P46934
Gene Symbols: NEDD4
Immunogen: Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
NEDD4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
NEDD4
Gene Alias:
NEDD4-1, RPF1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4734
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI7A1
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P46934
Gene Symbols:
NEDD4
Immunogen:
Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: MTHFR
Classification: Monoclonal
Conjugate: Unconjugated
Gene: MTHFR
Gene Alias: methylenetetrahydrofolate reductase
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4524
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI4C5
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P42898
Gene Symbols: MTHFR
Immunogen: Human recombit protein fragment corresponding to amino acids 1-230 of human MTHFR produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
MTHFR
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MTHFR
Gene Alias:
methylenetetrahydrofolate reductase
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4524
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI4C5
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P42898
Gene Symbols:
MTHFR
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-230 of human MTHFR produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: MMP11
Classification: Monoclonal
Conjugate: Unconjugated
Gene: MMP11
Gene Alias: SL-3, ST3, STMY3
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4320
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI2D7
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P24347
Gene Symbols: MMP11
Immunogen: Human recombit protein fragment corresponding to amino acids 239-488 of human MMP11 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
MMP11
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MMP11
Gene Alias:
SL-3, ST3, STMY3
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4320
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI2D7
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P24347
Gene Symbols:
MMP11
Immunogen:
Human recombit protein fragment corresponding to amino acids 239-488 of human MMP11 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1