50-168-4687

JAK3 Monoclonal Antibody (OTI1B4), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4687-Each-of-1 In Stock ₹ 43,217.21

50-168-4687 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

JAK3

Classification

Monoclonal

Conjugate

Unconjugated

Gene

JAK3

Gene Alias

JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3718

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

OTI1B4

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P52333

Gene Symbols

JAK3

Immunogen

Human recombit protein fragment corresponding to amino acids 811-1124 of human JAK3 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Janus Activating Kinase (JAK) is a number of related tyrosine kinases involved in cytoplasmic signal transduction
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • However, active JAK1 may be required for complex responses
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex.

Compare Similar Items

Show Difference

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OriGene

50-168-4687

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Antigen:
JAK3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
JAK3

Gene Alias:
JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3718

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI1B4

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P52333

Gene Symbols:
JAK3

Immunogen:
Human recombit protein fragment corresponding to amino acids 811-1124 of human JAK3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

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OriGene

50-168-4688

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Antigen:
BAZ1B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BAZ1B

Gene Alias:
WBSCR10, WBSCR9, WSTF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9031

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI3B8

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9UIG0

Gene Symbols:
BAZ1B

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-260 of human BAZ1B produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

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OriGene

50-168-4689

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Antigen:
CTSL1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CTSL

Gene Alias:
CATL, CTSL1, MEP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1514

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C7

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P07711

Gene Symbols:
CTSL

Immunogen:
Human recombit protein fragment corresponding to amino acids 114-333 of human CTSL produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

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OriGene

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Antigen:
CTSL1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CTSL

Gene Alias:
CATL, CTSL1, MEP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1514

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2C10

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P07711

Gene Symbols:
CTSL

Immunogen:
Human recombit protein fragment corresponding to amino acids 114-333 of human CTSL produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1