50-168-4746

DDX58 Rabbit anti-Human, Polyclonal, liquid, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4746-Each-of-1 In Stock ₹ 39,349.90

50-168-4746 - Each of 1

₹ 39,349.90

In Stock

Quantity

1

Base Price: ₹ 39,349.90

GST (18%): ₹ 7,082.982

Total Price: ₹ 46,432.882

Antigen

DDX58

Classification

Polyclonal

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

O95786

Gene Symbols

DDX58

Immunogen

Recombit protein of human DDX58

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

RIG-I, RIGI, RLR-1, SGMRT2

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23586

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5′-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and ultimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

Compare Similar Items

Show Difference

Img

OriGene

50-168-4746

--


Antigen:
DDX58

Classification:
Polyclonal

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O95786

Gene Symbols:
DDX58

Immunogen:
Recombit protein of human DDX58

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
RIG-I, RIGI, RLR-1, SGMRT2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23586

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4747

--


Antigen:
POLR2G

Classification:
Polyclonal

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P62487, P62488, P62489

Gene Symbols:
POLR2G

Immunogen:
Recombit protein of human POLR2G

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
POLR2G

Gene Alias:
RPB19, RPB7, hRPB19, hsRPB7

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117017, 5436, 67710

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4748

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Antigen:
FANCI

Classification:
Polyclonal

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9NVI1

Gene Symbols:
FANCI

Immunogen:
Recombit protein of human FANCI

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
FANCI

Gene Alias:
KIAA1794

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55215

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4749

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Antigen:
DUSP1

Classification:
Polyclonal

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P28562, P28563, Q64623

Gene Symbols:
Dusp1

Immunogen:
Recombit protein of human DUSP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
DUSP1

Gene Alias:
CL100, HVH1, MKP-1, MKP1, PTPN10

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114856, 1843, 19252

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid