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50-168-4819

NEDD4 Rabbit anti-Human, Polyclonal, liquid, OriGene

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-168-4819-Each-of-1 In Stock ₹ 39,349.90

50-168-4819 - Each of 1

₹ 39,349.90

In Stock

Quantity

1

Base Price: ₹ 39,349.90

GST (18%): ₹ 7,082.982

Total Price: ₹ 46,432.882

Antigen

NEDD4

Classification

Polyclonal

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P46934

Gene Symbols

NEDD4

Immunogen

Recombit protein of human NEDD4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

NEDD4

Gene Alias

NEDD4-1, RPF1

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4734

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein
  • It contains one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains
  • It is involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity
  • It acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53
  • It is also reported to be involved in the budding of many viruses and is the regulator of epithelial Na+ channels, which lead to arterial hypertension
  • NEDD4 protein is localized to the sarcolemmal region of muscle fibers
  • Increase in NEDD4 protein expression leads to unloaded and denervated muscles as well as a decrease in Notch1 expression
  • Hence it acts as down regulator of Notch-1 gene expression.

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OriGene

50-168-4819

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Antigen:
NEDD4
Classification:
Polyclonal
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P46934
Gene Symbols:
NEDD4
Immunogen:
Recombit protein of human NEDD4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
NEDD4
Gene Alias:
NEDD4-1, RPF1
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4734
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-4820

--

Antigen:
NFKB2
Classification:
Polyclonal
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q00653, Q9WTK5
Gene Symbols:
NFKB2
Immunogen:
Recombit protein of human NFKB2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
NFKB2
Gene Alias:
CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p49/p100; p52; nf?b
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18034, 4791
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-4823

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Antigen:
NUP214
Classification:
Polyclonal
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P35658, Q80U93
Gene Symbols:
NUP214
Immunogen:
Recombit protein of human NUP214
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
NUP214
Gene Alias:
CAIN, CAN
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
227720, 8021
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-4824

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Antigen:
PRKAB1
Classification:
Polyclonal
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9R078, Q9Y478
Gene Symbols:
Prkab1
Immunogen:
Recombit protein of human PRKAB1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
PRKAB1
Gene Alias:
AMPK, HAMPKb
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19079, 5564
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid