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50-168-4906

ERBB2 Mouse anti-Human, Mouse, Rat, Clone: UMAB36, lyophilized, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4906-Each-of-1 In Stock ₹ 62,958.47

50-168-4906 - Each of 1

₹ 62,958.47

In Stock

Quantity

1

Base Price: ₹ 62,958.47

GST (18%): ₹ 11,332.525

Total Price: ₹ 74,290.995

Antigen

ERBB2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ERBB2

Gene Alias

CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13866, 2064, 24337

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array, Western Blot

Clone

UMAB36

Formulation

PBS with 8% trehalose and no preservative

Gene Accession No.

P04626, P06494, P70424

Gene Symbols

ERBB2

Immunogen

Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Description

  • ErbB2 (Her2/neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR (epidermal growth factor receptor) family that regulates biological responses such as cell growth, differentiation, and tissue development
  • ErbB2 has no ligand binding domain of its own and cannot bind growth factors
  • However, ErbB2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase
  • Autophosphorylation of tyrosine 1139 on ErbB2 allows binding of Grb2 and the Src SH2 domain, which allows activation of the Ras, Raf, ERK1/2 and JAK/STAT signaling pathways, respectively
  • Alternative splicing of ErbB2 results in several transcript variants, some encoding different isoforms and others that have not been fully characterized
  • In humans, the gene encoding ERBB2 is present on chromosome 17
  • Amplification and/or overexpression of the ErbB2 gene has been reported in ovarian tumors, breast, lung and skin cancer.

Compare Similar Items

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OriGene

50-168-4906

--

Antigen:
ERBB2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13866, 2064, 24337
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array, Western Blot
Clone:
UMAB36
Formulation:
PBS with 8% trehalose and no preservative
Gene Accession No.:
P04626, P06494, P70424
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1

Img

OriGene

50-168-4908

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Antigen:
XRCC1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
XRCC1
Gene Alias:
RCC, SCAR26
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7515
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Clone:
UMAB40
Formulation:
PBS with 8% trehalose and no preservative
Gene Accession No.:
P18887
Gene Symbols:
XRCC1
Immunogen:
Full length human recombit protein of human XRCC1 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1

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OriGene

50-168-4909

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Antigen:
BMP4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
BMP4
Gene Alias:
BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
652
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB42
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
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Gene Symbols:
BMP4
Immunogen:
Recombit fragment expressed in E.coli corresponding to amino acids 293-408 of human BMP4
Quantity:
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Primary or Secondary:
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OriGene

50-168-4911

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Antigen:
ALDH1L1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ALDH1L1
Gene Alias:
10-FTHFDH, 10-fTHF, FDH, FTHFD
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100855730, 107747, 10840, 64392
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB43
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O75891, P28037, Q8R0Y6
Gene Symbols:
Aldh1l1, LOC100855730
Immunogen:
Full length human recombit protein of human ALDH1L1 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2b