50-168-5048
BUB1B Mouse anti-Human, Clone: UMAB7, liquid, UltraMAB™
Manufacturer: OriGene
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-5048-Each-of-1 | In Stock | ₹ 22,040.26 |
50-168-5048 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,040.26
GST (18%): ₹ 3,967.247
Total Price: ₹ 26,007.507
Antigen
BUB1B
Classification
Monoclonal
Concentration
0.5-1.0 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
O60566
Gene Symbols
BUB1B
Immunogen
Protein expressed in 293T cell transfected with human BUB1B expression vector
Quantity
30 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
UMAB7
Conjugate
Unconjugated
Gene
BUB1B
Gene Alias
BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
701
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Description
- BUBR1 is a member of the Ser/Thr protein kinase family
- It is a component of the mitotic checkpoint that delays anaphase until all chromosome are properly attached to the mitotic spindle
- Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to maligt transformations
- Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
- They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
- hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
- BUBR1 has been detected in human cancers
- It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.
Compare Similar Items
Show Difference
Antigen: BUB1B
Classification: Monoclonal
Concentration: 0.5-1.0 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O60566
Gene Symbols: BUB1B
Immunogen: Protein expressed in 293T cell transfected with human BUB1B expression vector
Quantity: 30 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: UMAB7
Conjugate: Unconjugated
Gene: BUB1B
Gene Alias: BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 701
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BUB1B
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O60566
Gene Symbols:
BUB1B
Immunogen:
Protein expressed in 293T cell transfected with human BUB1B expression vector
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB7
Conjugate:
Unconjugated
Gene:
BUB1B
Gene Alias:
BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
701
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ERCC1
Classification: Monoclonal
Concentration: 0.5-1.0 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P07992
Gene Symbols: ERCC1
Immunogen: Protein expressed in 293T cell transfected with human ERCC1 expression vector
Quantity: 30 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 4F9
Conjugate: Unconjugated
Gene: ERCC1
Gene Alias: COFS4, RAD10, UV20
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2067
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ERCC1
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P07992
Gene Symbols:
ERCC1
Immunogen:
Protein expressed in 293T cell transfected with human ERCC1 expression vector
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
4F9
Conjugate:
Unconjugated
Gene:
ERCC1
Gene Alias:
COFS4, RAD10, UV20
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2067
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: HP
Classification: Monoclonal
Concentration: 0.5-1.0 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P00738
Gene Symbols: HP
Immunogen: Full length human recombit protein of human HP produced in HEK293T cell.
Quantity: 30 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: UMAB10
Conjugate: Unconjugated
Gene: HP
Gene Alias: BP, HP2ALPHA2, HPA1S
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3240
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
HP
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P00738
Gene Symbols:
HP
Immunogen:
Full length human recombit protein of human HP produced in HEK293T cell.
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
UMAB10
Conjugate:
Unconjugated
Gene:
HP
Gene Alias:
BP, HP2ALPHA2, HPA1S
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3240
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SQSTM1
Classification: Monoclonal
Concentration: 0.5-1.0 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q13501
Gene Symbols: SQSTM1
Immunogen: Full length human recombit protein of human SQSTM1 produced in HEK293T cell.
Quantity: 30 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: UMAB12
Conjugate: Unconjugated
Gene: SQSTM1
Gene Alias: A170, DMRV, FTDALS3, NADGP, OSIL, PDB3, ZIP3, p60, p62, p62B
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8878
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SQSTM1
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q13501
Gene Symbols:
SQSTM1
Immunogen:
Full length human recombit protein of human SQSTM1 produced in HEK293T cell.
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB12
Conjugate:
Unconjugated
Gene:
SQSTM1
Gene Alias:
A170, DMRV, FTDALS3, NADGP, OSIL, PDB3, ZIP3, p60, p62, p62B
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8878
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid