Home Products Antibodies Primary Antibodies 50 168 5056
50-168-5056

Beta-catenin Mouse anti-Human, Mouse, Rat, Clone: UMAB15, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-5056-Each-of-1 In Stock ₹ 22,040.26

50-168-5056 - Each of 1

₹ 22,040.26

In Stock

Quantity

1

Base Price: ₹ 22,040.26

GST (18%): ₹ 3,967.247

Total Price: ₹ 26,007.507

Antigen

Beta-catenin

Classification

Monoclonal

Concentration

0.5-1.0 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P35222, Q02248, Q9WU82

Gene Symbols

Ctnnb1

Immunogen

Full length human recombit protein of human CTNNB1 produced in HEK293T cell.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

UMAB15

Conjugate

Unconjugated

Gene

CTNNB1

Gene Alias

CTNNB, EVR7, MRD19, armadillo

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12387, 1499, 84353

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
  • AJs are necessary for the creation and maintece of epithelial cell layers by regulating cell growth and adhesion between cells
  • Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
  • Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
  • The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
  • Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
  • A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
  • In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
  • The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.

Compare Similar Items

Show Difference

Img

OriGene

50-168-5056

--

Antigen:
Beta-catenin
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P35222, Q02248, Q9WU82
Gene Symbols:
Ctnnb1
Immunogen:
Full length human recombit protein of human CTNNB1 produced in HEK293T cell.
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB15
Conjugate:
Unconjugated
Gene:
CTNNB1
Gene Alias:
CTNNB, EVR7, MRD19, armadillo
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12387, 1499, 84353
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-5059

--

Antigen:
P53
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04637
Gene Symbols:
TP53
Immunogen:
Full length human recombit protein of human TP53 produced in HEK293T cell.
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB18
Conjugate:
Unconjugated
Gene:
TP53
Gene Alias:
BCC7, LFS1, P53, TRP53
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7157
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-5060

--

Antigen:
P53
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04637
Gene Symbols:
TP53
Immunogen:
Full length human recombit protein of human TP53 produced in HEK293T cell.
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB19
Conjugate:
Unconjugated
Gene:
TP53
Gene Alias:
BCC7, LFS1, P53, TRP53
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7157
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-5061

--

Antigen:
XPF
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q92889, Q9QZD4
Gene Symbols:
Ercc4
Immunogen:
Full length human recombit protein of human XPF produced in HEK293 cell.
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB20
Conjugate:
Unconjugated
Gene:
ERCC4
Gene Alias:
ERCC11, FANCQ, RAD1, XFEPS, XPF
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2072, 304719, 479842, 50505
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid