50-168-5167

CD2 Mouse anti-Human, Clone: UMAB86, lyophilized, UltraMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-168-5167-Each-of-1 In Stock ₹ 62,958.47

50-168-5167 - Each of 1

₹ 62,958.47

In Stock

Quantity

1

Base Price: ₹ 62,958.47

GST (18%): ₹ 11,332.525

Total Price: ₹ 74,290.995

Antigen

CD2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CD2

Gene Alias

LFA-2, SRBC, T11

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

914

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Peptide Array

Clone

UMAB86

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P06729

Gene Symbols

CD2

Immunogen

Full length human recombit protein of human CD2 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
  • CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
  • Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
  • The interaction betwee CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
  • Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
  • Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
  • Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
  • CD2 deficiency reduces intestinal inflammation and helps to control infection
  • Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.

Compare Similar Items

Show Difference

Img

OriGene

50-168-5167

--


Antigen:
CD2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD2

Gene Alias:
LFA-2, SRBC, T11

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
914

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Peptide Array

Clone:
UMAB86

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P06729

Gene Symbols:
CD2

Immunogen:
Full length human recombit protein of human CD2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-5168

--


Antigen:
WFDC2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
WFDC2

Gene Alias:
EDDM4, HE4, WAP5, dJ461P17.6

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10406

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB87

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q14508

Gene Symbols:
WFDC2

Immunogen:
Human recombit protein fragment corresponding to amino acids 31-124 of human WFDC2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-5170

--


Antigen:
WFDC2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
WFDC2

Gene Alias:
EDDM4, HE4, WAP5, dJ461P17.6

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10406

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB88

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q14508

Gene Symbols:
WFDC2

Immunogen:
Human recombit protein fragment corresponding to amino acids 31-124 of human WFDC2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-5173

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Antigen:
FOXP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FOXP1

Gene Alias:
12CC4, HSPC215, MFH, QRF1, hFKH1B

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108655, 27086, 297480

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array

Clone:
UMAB89

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P58462, Q498D1, Q9H334

Gene Symbols:
Foxp1

Immunogen:
Full length human recombit protein of human FOXP1 produced in SF9 cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1